8452


Homo sapiens (NCBI)

Features
Gene ID: 8452
  
Biological name :
  
Synonyms : CUL3 / CUL-3|PHA2E / cullin 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 201370_s_at (Human Genome U133 Plus 2.0 Array)   201371_s_at (Human Genome U133 Plus 2.0 Array)   201372_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 380714663
RefSeq - 380714665
RefSeq - 4503165
RefSeq - 767920144
RefSeq - 767920146
RefSeq - 767920148
RefSeq - 767920150
RefSeq - NC_000002.12
RefSeq - NG_032169.1
RefSeq - NP_001244126.1
RefSeq - NP_001244127.1
RefSeq - NP_003581.1
RefSeq - XP_006712863.2
RefSeq - XP_011510296.1
RefSeq - XP_011510297.1
RefSeq - XP_011510298.1
RefSeq - NM_001257197.1
RefSeq - NM_001257198.1
RefSeq - NM_003590.4
RefSeq - XM_011511994.3
RefSeq - XM_011511995.1
RefSeq - XM_011511996.2
RefSeq - XM_006712800.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000036257 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000082 G1/S transition of mitotic cell cycle TAS
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0000165 MAPK cascade TAS
 biological_processGO:0000209 protein polyubiquitination IDA
 biological_processGO:0001831 trophectodermal cellular morphogenesis IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IDA
 biological_processGO:0006513 protein monoubiquitination IDA
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport IDA
 biological_processGO:0007050 cell cycle arrest TAS
 biological_processGO:0007080 mitotic metaphase plate congression IMP
 biological_processGO:0007229 integrin-mediated signaling pathway ISS
 biological_processGO:0007369 gastrulation IEA
 biological_processGO:0008284 positive regulation of cell proliferation TAS
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0016477 cell migration IMP
 biological_processGO:0016567 protein ubiquitination IDA
 biological_processGO:0017145 stem cell division ISS
 biological_processGO:0030030 cell projection organization IEA
 biological_processGO:0031145 anaphase-promoting complex-dependent catabolic process IDA
 biological_processGO:0031398 positive regulation of protein ubiquitination IGI
 biological_processGO:0031648 protein destabilization IGI
 biological_processGO:0032467 positive regulation of cytokinesis IMP
 biological_processGO:0035024 negative regulation of Rho protein signal transduction IMP
 biological_processGO:0040016 embryonic cleavage ISS
 biological_processGO:0043149 stress fiber assembly IMP
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IDA
 biological_processGO:0043687 post-translational protein modification TAS
 biological_processGO:0044346 fibroblast apoptotic process IEA
 biological_processGO:0045842 positive regulation of mitotic metaphase/anaphase transition IMP
 biological_processGO:0048208 COPII vesicle coating IMP
 biological_processGO:0071630 nuclear protein quality control by the ubiquitin-proteasome system IDA
 biological_processGO:0072576 liver morphogenesis IEA
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway TAS
 biological_processGO:0097193 intrinsic apoptotic signaling pathway TAS
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005827 polar microtubule IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0031461 cullin-RING ubiquitin ligase complex IBA
 cellular_componentGO:0031463 Cul3-RING ubiquitin ligase complex IDA
 cellular_componentGO:0036126 sperm flagellum IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IDA
 molecular_functionGO:0005112 Notch binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030332 cyclin binding IEA
 molecular_functionGO:0031208 POZ domain binding IDA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IBA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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