8517


Homo sapiens (NCBI)

Features
Gene ID: 8517
  
Biological name :
  
Synonyms : AMCBX1|FIP-3|FIP3|Fip3p|IKK-gamma|IKKAP1|IKKG|IMD33|IP|IP1|IP2|IPD2|NEMO|ZC2HC9 / IKBKG / inhibitor of nuclear factor kappa B kinase subunit gamma
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 209929_s_at (Human Genome U133 Plus 2.0 Array)   36004_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1008909414
RefSeq - 1008909416
RefSeq - 153792133
RefSeq - 223671870
RefSeq - 223671872
RefSeq - 4504631
RefSeq - NC_000023.11
RefSeq - NG_009896.1
RefSeq - NP_001093326.2
RefSeq - NP_001093327.1
RefSeq - NP_001138727.1
RefSeq - NP_001308325.1
RefSeq - NP_001308326.1
RefSeq - NP_003630.1
RefSeq - NM_001099856.4
RefSeq - NM_001099857.2
RefSeq - NM_001145255.2
RefSeq - NM_001321396.1
RefSeq - NM_001321397.1
RefSeq - NM_003639.4
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000269335 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000187 activation of MAPK activity TAS
 biological_processGO:0002223 stimulatory C-type lectin receptor signaling pathway TAS
 biological_processGO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent TAS
 biological_processGO:0002756 MyD88-independent toll-like receptor signaling pathway TAS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006915 apoptotic process TAS
 biological_processGO:0006954 inflammatory response TAS
 biological_processGO:0006955 immune response TAS
 biological_processGO:0006974 cellular response to DNA damage stimulus IMP
 biological_processGO:0007249 I-kappaB kinase/NF-kappaB signaling TAS
 biological_processGO:0007254 JNK cascade TAS
 biological_processGO:0009615 response to virus TAS
 biological_processGO:0010803 regulation of tumor necrosis factor-mediated signaling pathway TAS
 biological_processGO:0016032 viral process IEA
 biological_processGO:0016239 positive regulation of macroautophagy ISS
 biological_processGO:0016579 protein deubiquitination TAS
 biological_processGO:0035666 TRIF-dependent toll-like receptor signaling pathway TAS
 biological_processGO:0038095 Fc-epsilon receptor signaling pathway TAS
 biological_processGO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling IBA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling TAS
 biological_processGO:0043276 anoikis ISS
 biological_processGO:0045087 innate immune response TAS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0050852 T cell receptor signaling pathway TAS
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity TAS
 biological_processGO:0051403 stress-activated MAPK cascade TAS
 biological_processGO:0051650 establishment of vesicle localization IMP
 biological_processGO:0070423 nucleotide-binding oligomerization domain containing signaling pathway TAS
 biological_processGO:0070498 interleukin-1-mediated signaling pathway TAS
 biological_processGO:1901215 negative regulation of neuron death TAS
 cellular_componentGO:0000151 ubiquitin ligase complex IPI
 cellular_componentGO:0000922 spindle pole IDA
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0008385 IkappaB kinase complex TAS
 cellular_componentGO:0072686 mitotic spindle IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019904 protein domain specific binding IPI
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0042975 peroxisome proliferator activated receptor binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IDA
 molecular_functionGO:0070530 K63-linked polyubiquitin modification-dependent protein binding IBA
 molecular_functionGO:1990450 linear polyubiquitin binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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