8678


Homo sapiens (NCBI)

Features
Gene ID: 8678
  
Biological name :
  
Synonyms : ATG6|VPS30|beclin1 / beclin 1 / BECN1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1561652_at (Human Genome U133 Plus 2.0 Array)   208945_s_at (Human Genome U133 Plus 2.0 Array)   208946_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - XP_016880753.1
RefSeq - 1034601840
RefSeq - 1034601843
RefSeq - 4502395
RefSeq - 530413037
RefSeq - 530413039
RefSeq - 767996330
RefSeq - 929524267
RefSeq - 929524269
RefSeq - 929524271
RefSeq - NC_000017.11
RefSeq - NP_001300927.1
RefSeq - NP_001300928.1
RefSeq - NP_001300929.1
RefSeq - NP_003757.1
RefSeq - XP_005257816.1
RefSeq - XP_005257817.1
RefSeq - XP_011523723.1
RefSeq - XP_016880751.1
RefSeq - XP_016880752.1
RefSeq - 1034601838
RefSeq - NM_001313998.1
RefSeq - NM_001313999.1
RefSeq - NM_001314000.1
RefSeq - NM_003766.4
RefSeq - XM_011525421.2
RefSeq - XM_017025262.2
RefSeq - XM_017025263.2
RefSeq - XM_017025264.2
RefSeq - XM_005257759.3
RefSeq - XM_005257760.4
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000126581 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000045 autophagosome assembly ISS
 biological_processGO:0000422 autophagy of mitochondrion IMP
 biological_processGO:0000423 mitophagy IMP
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0006914 autophagy IMP
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006968 cellular defense response TAS
 biological_processGO:0006995 cellular response to nitrogen starvation IBA
 biological_processGO:0007040 lysosome organization IEA
 biological_processGO:0007080 mitotic metaphase plate congression IMP
 biological_processGO:0007568 aging IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0010040 response to iron(II) ion IEA
 biological_processGO:0010288 response to lead ion IEA
 biological_processGO:0010613 positive regulation of cardiac muscle hypertrophy IEA
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling NAS
 biological_processGO:0016032 viral process IEA
 biological_processGO:0016236 macroautophagy TAS
 biological_processGO:0016579 protein deubiquitination TAS
 biological_processGO:0032258 protein localization by the Cvt pathway IBA
 biological_processGO:0032465 regulation of cytokinesis IMP
 biological_processGO:0032801 receptor catabolic process IMP
 biological_processGO:0033197 response to vitamin E IEA
 biological_processGO:0034198 cellular response to amino acid starvation IEA
 biological_processGO:0042149 cellular response to glucose starvation ISS
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0043652 engulfment of apoptotic cell IEA
 biological_processGO:0045022 early endosome to late endosome transport IMP
 biological_processGO:0045324 late endosome to vacuole transport IBA
 biological_processGO:0048666 neuron development IEA
 biological_processGO:0050435 amyloid-beta metabolic process IEA
 biological_processGO:0050790 regulation of catalytic activity IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:0060548 negative regulation of cell death IMP
 biological_processGO:0070301 cellular response to hydrogen peroxide IEA
 biological_processGO:0071275 cellular response to aluminum ion IEA
 biological_processGO:0071280 cellular response to copper ion IEA
 biological_processGO:0071364 cellular response to epidermal growth factor stimulus IEA
 biological_processGO:0098780 response to mitochondrial depolarisation IMP
 biological_processGO:1902425 positive regulation of attachment of mitotic spindle microtubules to kinetochore IMP
 biological_processGO:1902902 negative regulation of autophagosome assembly IEA
 biological_processGO:1905672 negative regulation of lysosome organization IEA
 biological_processGO:2000378 negative regulation of reactive oxygen species metabolic process IEA
 biological_processGO:2000786 positive regulation of autophagosome assembly IEA
 cellular_componentGO:0000407 phagophore assembly site IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005739 mitochondrion IMP
 cellular_componentGO:0005768 endosome IDA
 cellular_componentGO:0005776 autophagosome IEA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005802 trans-Golgi network IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0019898 extrinsic component of membrane IDA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0031966 mitochondrial membrane IEA
 cellular_componentGO:0034271 phosphatidylinositol 3-kinase complex, class III, type I IBA
 cellular_componentGO:0034272 phosphatidylinositol 3-kinase complex, class III, type II IBA
 cellular_componentGO:0035032 phosphatidylinositol 3-kinase complex, class III ISS
 cellular_componentGO:0045335 phagocytic vesicle IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0043548 phosphatidylinositol 3-kinase binding IPI
 molecular_functionGO:0051020 GTPase binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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