8772


Homo sapiens (NCBI)

Features
Gene ID: 8772
  
Biological name :
  
Synonyms : FADD / Fas associated via death domain / GIG3|MORT1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 202535_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 4505229
RefSeq - NC_000011.10
RefSeq - NG_027966.1
RefSeq - NP_003815.1
RefSeq - NM_003824.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000168040 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001916 positive regulation of T cell mediated cytotoxicity ISS
 biological_processGO:0002821 positive regulation of adaptive immune response ISS
 biological_processGO:0006915 apoptotic process IMP
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process TAS
 biological_processGO:0007166 cell surface receptor signaling pathway TAS
 biological_processGO:0008625 extrinsic apoptotic signaling pathway via death domain receptors TAS
 biological_processGO:0016032 viral process IEA
 biological_processGO:0032729 positive regulation of interferon-gamma production ISS
 biological_processGO:0032757 positive regulation of interleukin-8 production IDA
 biological_processGO:0032760 positive regulation of tumor necrosis factor production IDA
 biological_processGO:0033077 T cell differentiation in thymus ISS
 biological_processGO:0034138 toll-like receptor 3 signaling pathway TAS
 biological_processGO:0035666 TRIF-dependent toll-like receptor signaling pathway TAS
 biological_processGO:0036462 TRAIL-activated apoptotic signaling pathway IDA
 biological_processGO:0042104 positive regulation of activated T cell proliferation ISS
 biological_processGO:0043029 T cell homeostasis ISS
 biological_processGO:0043065 positive regulation of apoptotic process IMP
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IEP
 biological_processGO:0043278 response to morphine IEA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045651 positive regulation of macrophage differentiation IMP
 biological_processGO:0045862 positive regulation of proteolysis IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0048148 behavioral response to cocaine IEA
 biological_processGO:0048535 lymph node development ISS
 biological_processGO:0048536 spleen development ISS
 biological_processGO:0048538 thymus development ISS
 biological_processGO:0051607 defense response to virus IMP
 biological_processGO:0060340 positive regulation of type I interferon-mediated signaling pathway IMP
 biological_processGO:0060546 negative regulation of necroptotic process IEA
 biological_processGO:0070236 negative regulation of activation-induced cell death of T cells ISS
 biological_processGO:0071260 cellular response to mechanical stimulus IEP
 biological_processGO:0071550 death-inducing signaling complex assembly TAS
 biological_processGO:0097049 motor neuron apoptotic process IEA
 biological_processGO:0097190 apoptotic signaling pathway TAS
 biological_processGO:0097191 extrinsic apoptotic signaling pathway TAS
 biological_processGO:0097192 extrinsic apoptotic signaling pathway in absence of ligand IEA
 biological_processGO:0097202 activation of cysteine-type endopeptidase activity IDA
 biological_processGO:0097527 necroptotic signaling pathway IMP
 biological_processGO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors TAS
 biological_processGO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors TAS
 biological_processGO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors IEA
 biological_processGO:2000454 positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation ISS
 biological_processGO:2001238 positive regulation of extrinsic apoptotic signaling pathway IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0031264 death-inducing signaling complex TAS
 cellular_componentGO:0031265 CD95 death-inducing signaling complex IDA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0044297 cell body IEA
 cellular_componentGO:0045121 membrane raft IEA
 cellular_componentGO:0097342 ripoptosome IDA
 molecular_functionGO:0002020 protease binding IPI
 molecular_functionGO:0005123 death receptor binding IEA
 molecular_functionGO:0005164 tumor necrosis factor receptor binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0032813 tumor necrosis factor receptor superfamily binding IPI
 molecular_functionGO:0033612 receptor serine/threonine kinase binding IEA
 molecular_functionGO:0035877 death effector domain binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0044877 protein-containing complex binding IEA
 molecular_functionGO:0089720 caspase binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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