90


Homo sapiens (NCBI)

Features
Gene ID: 90
  
Biological name :
  
Synonyms : activin A receptor type 1 / ACTRI|ACVR1A|ACVRLK2|ALK2|FOP|SKR1|TSRI / ACVR1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 203935_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1111244438
RefSeq - 1111244440
RefSeq - 1111244442
RefSeq - 1111244444
RefSeq - 1111244446
RefSeq - 166235898
RefSeq - 4501895
RefSeq - 578805100
RefSeq - 767920419
RefSeq - NC_000002.12
RefSeq - NG_008004.1
RefSeq - NP_001096.1
RefSeq - NP_001104537.1
RefSeq - NP_001334592.1
RefSeq - NP_001334593.1
RefSeq - NP_001334594.1
RefSeq - NP_001334595.1
RefSeq - NP_001334596.1
RefSeq - XP_006712888.1
RefSeq - XP_011510410.1
RefSeq - NM_001105.4
RefSeq - NM_001111067.2
RefSeq - NM_001347663.1
RefSeq - NM_001347664.1
RefSeq - NM_001347665.1
RefSeq - NM_001347666.1
RefSeq - NM_001347667.1
RefSeq - XM_011512108.3
RefSeq - XM_006712825.4
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000115170 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000082 G1/S transition of mitotic cell cycle IMP
 biological_processGO:0001569 branching involved in blood vessel morphogenesis IEA
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0001702 gastrulation with mouth forming second IEA
 biological_processGO:0001707 mesoderm formation IEA
 biological_processGO:0001755 neural crest cell migration IEA
 biological_processGO:0002526 acute inflammatory response IEA
 biological_processGO:0003143 embryonic heart tube morphogenesis IMP
 biological_processGO:0003148 outflow tract septum morphogenesis ISS
 biological_processGO:0003181 atrioventricular valve morphogenesis ISS
 biological_processGO:0003183 mitral valve morphogenesis IMP
 biological_processGO:0003203 endocardial cushion morphogenesis ISS
 biological_processGO:0003274 endocardial cushion fusion ISS
 biological_processGO:0003289 atrial septum primum morphogenesis ISS
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway IDA
 biological_processGO:0007281 germ cell development IEA
 biological_processGO:0007368 determination of left/right symmetry IEA
 biological_processGO:0007389 pattern specification process IBA
 biological_processGO:0007507 heart development IBA
 biological_processGO:0009968 negative regulation of signal transduction IMP
 biological_processGO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation ISS
 biological_processGO:0018107 peptidyl-threonine phosphorylation IDA
 biological_processGO:0030278 regulation of ossification IMP
 biological_processGO:0030335 positive regulation of cell migration IGI
 biological_processGO:0030501 positive regulation of bone mineralization IMP
 biological_processGO:0030509 BMP signaling pathway IDA
 biological_processGO:0032924 activin receptor signaling pathway IMP
 biological_processGO:0032926 negative regulation of activin receptor signaling pathway IMP
 biological_processGO:0045669 positive regulation of osteoblast differentiation IMP
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISS
 biological_processGO:0051145 smooth muscle cell differentiation IEA
 biological_processGO:0060037 pharyngeal system development IEA
 biological_processGO:0060389 pathway-restricted SMAD protein phosphorylation IDA
 biological_processGO:0060412 ventricular septum morphogenesis ISS
 biological_processGO:0060923 cardiac muscle cell fate commitment IMP
 biological_processGO:0061312 BMP signaling pathway involved in heart development ISS
 biological_processGO:0061445 endocardial cushion cell fate commitment IMP
 biological_processGO:0071773 cellular response to BMP stimulus IMP
 biological_processGO:1905007 positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation ISS
 biological_processGO:2000017 positive regulation of determination of dorsal identity IDA
 biological_processGO:2001237 negative regulation of extrinsic apoptotic signaling pathway IMP
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0043235 receptor complex IBA
 cellular_componentGO:0045177 apical part of cell IEA
 cellular_componentGO:0048179 activin receptor complex IDA
 molecular_functionGO:0004672 protein kinase activity IDA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IDA
 molecular_functionGO:0004675 transmembrane receptor protein serine/threonine kinase activity NAS
 molecular_functionGO:0005024 transforming growth factor beta-activated receptor activity IBA
 molecular_functionGO:0005025 transforming growth factor beta receptor activity, type I IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IDA
 molecular_functionGO:0016361 activin receptor activity, type I IDA
 molecular_functionGO:0017046 peptide hormone binding NAS
 molecular_functionGO:0019838 growth factor binding IBA
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046332 SMAD binding IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0048185 activin binding IDA
 molecular_functionGO:0050431 transforming growth factor beta binding IDA
 molecular_functionGO:0098821 BMP receptor activity IBA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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