972


Homo sapiens (NCBI)

Features
Gene ID: 972
  
Biological name :
  
Synonyms : CD74 / CD74 molecule / DHLAG|HLADG|II|Ia-GAMMA|p33
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1567627_at (Human Genome U133 Plus 2.0 Array)   1567628_at (Human Genome U133 Plus 2.0 Array)   209619_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - NP_001351012.1
RefSeq - NP_001351013.1
RefSeq - NP_004346.1
RefSeq - 68448544
RefSeq - NC_000005.10
RefSeq - NG_029730.1
RefSeq - XP_016865578.1
RefSeq - XP_016865579.1
RefSeq - 1034646880
RefSeq - 1034646882
RefSeq - 10835071
RefSeq - 1395777147
RefSeq - 1395777166
RefSeq - 68448537
RefSeq - NP_001020329.1
RefSeq - NP_001020330.1
RefSeq - XR_002956198.1
RefSeq - NM_001025158.2
RefSeq - NM_001025159.2
RefSeq - NM_001364083.1
RefSeq - NM_001364084.1
RefSeq - NM_004355.3
RefSeq - NR_157074.1
RefSeq - XM_017010089.2
RefSeq - XM_017010090.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000019582 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000187 activation of MAPK activity IEA
 biological_processGO:0001516 prostaglandin biosynthetic process IDA
 biological_processGO:0001934 positive regulation of protein phosphorylation IDA
 biological_processGO:0001961 positive regulation of cytokine-mediated signaling pathway IMP
 biological_processGO:0002606 positive regulation of dendritic cell antigen processing and presentation IEA
 biological_processGO:0002792 negative regulation of peptide secretion IDA
 biological_processGO:0002830 positive regulation of type 2 immune response IEA
 biological_processGO:0002906 negative regulation of mature B cell apoptotic process IEA
 biological_processGO:0006886 intracellular protein transport ISS
 biological_processGO:0006952 defense response IEA
 biological_processGO:0007165 signal transduction IDA
 biological_processGO:0008283 cell proliferation IDA
 biological_processGO:0016064 immunoglobulin mediated immune response ISS
 biological_processGO:0019883 antigen processing and presentation of endogenous antigen NAS
 biological_processGO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II TAS
 biological_processGO:0030890 positive regulation of B cell proliferation IMP
 biological_processGO:0033674 positive regulation of kinase activity IDA
 biological_processGO:0035691 macrophage migration inhibitory factor signaling pathway IEA
 biological_processGO:0043030 regulation of macrophage activation NAS
 biological_processGO:0043066 negative regulation of apoptotic process IDA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IDA
 biological_processGO:0043410 positive regulation of MAPK cascade IDA
 biological_processGO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator IDA
 biological_processGO:0045058 T cell selection NAS
 biological_processGO:0045059 positive thymic T cell selection IEA
 biological_processGO:0045060 negative thymic T cell selection IEA
 biological_processGO:0045581 negative regulation of T cell differentiation IEA
 biological_processGO:0045582 positive regulation of T cell differentiation IEA
 biological_processGO:0045657 positive regulation of monocyte differentiation IDA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0046598 positive regulation of viral entry into host cell IDA
 biological_processGO:0048146 positive regulation of fibroblast proliferation IMP
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0050900 leukocyte migration TAS
 biological_processGO:0051085 chaperone cofactor-dependent protein refolding IEA
 biological_processGO:0051290 protein heterotetramerization IDA
 biological_processGO:0060907 positive regulation of macrophage cytokine production ISS
 biological_processGO:0065003 protein-containing complex assembly ISS
 biological_processGO:0070206 protein trimerization IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IMP
 biological_processGO:0090023 positive regulation of neutrophil chemotaxis ISS
 biological_processGO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IMP
 biological_processGO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production ISS
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005622 intracellular TAS
 cellular_componentGO:0005765 lysosomal membrane TAS
 cellular_componentGO:0005771 multivesicular body IEA
 cellular_componentGO:0005773 vacuole IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0012507 ER to Golgi transport vesicle membrane TAS
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0016021 integral component of membrane IDA
 cellular_componentGO:0030658 transport vesicle membrane TAS
 cellular_componentGO:0030666 endocytic vesicle membrane TAS
 cellular_componentGO:0030669 clathrin-coated endocytic vesicle membrane TAS
 cellular_componentGO:0032588 trans-Golgi network membrane TAS
 cellular_componentGO:0035692 macrophage migration inhibitory factor receptor complex IDA
 cellular_componentGO:0035693 NOS2-CD74 complex IEA
 cellular_componentGO:0042613 MHC class II protein complex ISS
 cellular_componentGO:0043202 lysosomal lumen TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0071556 integral component of lumenal side of endoplasmic reticulum membrane TAS
 molecular_functionGO:0001540 amyloid-beta binding IPI
 molecular_functionGO:0004896 cytokine receptor activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019955 cytokine binding IPI
 molecular_functionGO:0023026 MHC class II protein complex binding IDA
 molecular_functionGO:0035718 macrophage migration inhibitory factor binding IPI
 molecular_functionGO:0042289 MHC class II protein binding NAS
 molecular_functionGO:0042609 CD4 receptor binding IPI
 molecular_functionGO:0042658 MHC class II protein binding, via antigen binding groove IDA
 molecular_functionGO:0042802 identical protein binding TAS
 molecular_functionGO:0044183 protein binding involved in protein folding IDA
 molecular_functionGO:0050998 nitric-oxide synthase binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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