9971


Homo sapiens (NCBI)

Features
Gene ID: 9971
  
Biological name :
  
Synonyms : BAR|FXR|HRR-1|HRR1|PFIC5|RIP14 / NR1H4 / nuclear receptor subfamily 1 group H member 4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1554375_a_at (Human Genome U133 Plus 2.0 Array)   206340_at (Human Genome U133 Plus 2.0 Array)   243800_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 332801015
RefSeq - 332801017
RefSeq - 332801019
RefSeq - 332801065
RefSeq - 332801067
RefSeq - 4826980
RefSeq - 578824525
RefSeq - 767976073
RefSeq - 767976075
RefSeq - 767976078
RefSeq - NC_000012.12
RefSeq - NG_029843.1
RefSeq - NP_001193906.1
RefSeq - NP_001193907.1
RefSeq - NP_001193908.1
RefSeq - NP_001193921.1
RefSeq - NP_001193922.1
RefSeq - NP_005114.1
RefSeq - XP_006719782.1
RefSeq - XP_011537342.1
RefSeq - XP_011537343.1
RefSeq - XP_011537344.1
RefSeq - XM_011539041.2
RefSeq - NM_001206977.1
RefSeq - NM_001206978.1
RefSeq - NM_001206979.1
RefSeq - NM_001206992.1
RefSeq - NM_001206993.1
RefSeq - NM_005123.3
RefSeq - XM_011539042.1
RefSeq - NR_135146.1
RefSeq - XM_006719719.2
RefSeq - XM_011539040.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000012504 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II ISS
 biological_processGO:0001080 nitrogen catabolite activation of transcription from RNA polymerase II promoter IC
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter TAS
 biological_processGO:0006629 lipid metabolic process IBA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0007043 cell-cell junction assembly IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007219 Notch signaling pathway IEA
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0008206 bile acid metabolic process IEA
 biological_processGO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway IEA
 biological_processGO:0010988 regulation of low-density lipoprotein particle clearance IDA
 biological_processGO:0015721 bile acid and bile salt transport TAS
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030522 intracellular receptor signaling pathway ISS
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity IEA
 biological_processGO:0032692 negative regulation of interleukin-1 production IEA
 biological_processGO:0032703 negative regulation of interleukin-2 production IEA
 biological_processGO:0032715 negative regulation of interleukin-6 production IEA
 biological_processGO:0033993 response to lipid IBA
 biological_processGO:0034142 toll-like receptor 4 signaling pathway IDA
 biological_processGO:0034162 toll-like receptor 9 signaling pathway IEA
 biological_processGO:0034255 regulation of urea metabolic process ISS
 biological_processGO:0034971 histone H3-R17 methylation IDA
 biological_processGO:0035356 cellular triglyceride homeostasis IDA
 biological_processGO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus IEA
 biological_processGO:0038183 bile acid signaling pathway TAS
 biological_processGO:0038185 intracellular bile acid receptor signaling pathway IDA
 biological_processGO:0042593 glucose homeostasis IEA
 biological_processGO:0042632 cholesterol homeostasis IEA
 biological_processGO:0042742 defense response to bacterium IEA
 biological_processGO:0043066 negative regulation of apoptotic process IDA
 biological_processGO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling IDA
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0046628 positive regulation of insulin receptor signaling pathway IEA
 biological_processGO:0050728 negative regulation of inflammatory response IEA
 biological_processGO:0055088 lipid homeostasis IBA
 biological_processGO:0055089 fatty acid homeostasis IEA
 biological_processGO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus IDA
 biological_processGO:0070857 regulation of bile acid biosynthetic process TAS
 biological_processGO:0070858 negative regulation of bile acid biosynthetic process IDA
 biological_processGO:0071222 cellular response to lipopolysaccharide IEA
 biological_processGO:0071398 cellular response to fatty acid IDA
 biological_processGO:0071417 cellular response to organonitrogen compound ISS
 biological_processGO:0071638 negative regulation of monocyte chemotactic protein-1 production IEA
 biological_processGO:0072615 interleukin-17 secretion IDA
 biological_processGO:0090181 regulation of cholesterol metabolic process TAS
 biological_processGO:1902714 negative regulation of interferon-gamma secretion IDA
 biological_processGO:1904179 positive regulation of adipose tissue development IEA
 biological_processGO:1904468 negative regulation of tumor necrosis factor secretion IDA
 biological_processGO:1905695 positive regulation of phosphatidic acid biosynthetic process IDA
 biological_processGO:2000213 positive regulation of glutamate metabolic process ISS
 biological_processGO:2001250 positive regulation of ammonia assimilation cycle IEA
 biological_processGO:2001275 positive regulation of glucose import in response to insulin stimulus IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005719 nuclear euchromatin IDA
 cellular_componentGO:0090575 RNA polymerase II transcription factor complex IBA
 molecular_functionGO:0000976 transcription regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001076 transcription factor activity, RNA polymerase II transcription factor binding IBA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding IDA
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding IDA
 molecular_functionGO:0003707 steroid hormone receptor activity IEA
 molecular_functionGO:0003713 transcription coactivator activity TAS
 molecular_functionGO:0003714 transcription corepressor activity TAS
 molecular_functionGO:0004879 nuclear receptor activity ISS
 molecular_functionGO:0004887 thyroid hormone receptor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding IBA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0008289 lipid binding IBA
 molecular_functionGO:0016922 nuclear receptor binding TAS
 molecular_functionGO:0030374 nuclear receptor transcription coactivator activity IBA
 molecular_functionGO:0032052 bile acid binding TAS
 molecular_functionGO:0038181 bile acid receptor activity TAS
 molecular_functionGO:0043565 sequence-specific DNA binding IDA
 molecular_functionGO:0046965 retinoid X receptor binding IEA
 molecular_functionGO:0098531 transcription factor activity, direct ligand regulated sequence-specific DNA binding IBA
 molecular_functionGO:1902122 chenodeoxycholic acid binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr