ENSDARG00000004262


Danio rerio

Features
Gene ID: ENSDARG00000004262
  
Biological name :cyp46a1.2
  
Synonyms : cyp46a1.2 / cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 2
  
Possible biological names infered from orthology : Cholesterol 24-hydroxylase / CYP46A1 / cytochrome P450 family 46 subfamily A member 1 / Q9WVK8 / Q9Y6A2
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 5237286
Gene end: 5254610
  
Corresponding Affymetrix probe sets: Dr.17457.1.A1_at (Zebrafish Array)   DrAffx.2.57.A1_at (Zebrafish Array)   NM_200461_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000057698
NCBI entrez gene - 393433     See in Manteia.
RefSeq - NM_200461
RefSeq Peptide - NP_956755
swissprot - F1Q9I2
ZFIN ID - ZDB-GENE-040426-1184
Ensembl - ENSDARG00000004262
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CYP46A1ENSGALG00000011162Gallus gallus
 Q9Y6A2ENSG00000036530Homo sapiens
 Q9WVK8ENSMUSG00000021259Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cyp46a1.4 / cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 4 / Q9Y6A2* / CYP46A1* / cytochrome P450 family 46 subfamily A member 1*ENSDARG0000011382094
cyp46a1.1 / cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 1 / Q9Y6A2* / CYP46A1* / cytochrome P450 family 46 subfamily A member 1*ENSDARG0000009347792
cyp46a1.1 / cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 1 / Q9Y6A2* / Q9WVK8* / CYP46A1* / Cholesterol 24-hydroxylase * / cytochrome P450 family 46 subfamily A member 1*ENSDARG0000001213790
cyp46a1.3 / cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 3 / Q9Y6A2* / CYP46A1* / cytochrome P450 family 46 subfamily A member 1*ENSDARG0000008917775
cyp3a65 / cytochrome P450, family 3, subfamily A, polypeptide 65 / CYP3A4* / CYP3A5* / CYP3A7* / P08684* / P20815* / P24462* / Q9HB55* / CYP3A43* / CYP3A7-CYP3A51P* / CYP3A7-CYP3A51P readth...ENSDARG0000010329526
cyp3c3 / cytochrome P450, family 3, subfamily c, polypeptide 3 / P20815* / P08684* / O09158* / P24462* / Q64459* / Q9JMA7* / CYP3A5* / Q9HB55* / CYP3A4* / CYP3A7* / Q64481* / Q64464* / Cyp3...ENSDARG0000003787325
cyp3c4 / cytochrome P450, family 3, subfamily C, polypeptide 4 / P20815* / P08684* / O09158* / P24462* / Q64459* / Q9JMA7* / CYP3A5* / Q9HB55* / CYP3A4* / CYP3A7* / Q64481* / Q64464* / Cyp3...ENSDARG0000007002124
cyp3c1 / cytochrome P450, family 3, subfamily c, polypeptide 1 / P20815* / P08684* / O09158* / P24462* / Q64459* / Q9JMA7* / CYP3A5* / Q9HB55* / CYP3A4* / CYP3A7* / Q64481* / Q64464* / Cyp3...ENSDARG0000001557524
cyp3c3 / cyp3c2 / cytochrome P450, family 3, subfamily c, polypeptide 2 / P08684* / O09158* / Q64459* / Q9JMA7* / CYP3A5* / Q9HB55* / CYP3A4* / CYP3A7* / Q64481* / Q64464* / P20815* / P2446...ENSDARG0000003787423
tbxas1 / thromboxane A synthase 1 (platelet) / P24557* / P36423* / thromboxane A synthase 1*ENSDARG0000000224923
cyp27a1.2 / cytochrome P450, family 27, subfamily A, polypeptide 1, gene 2 / Q02318* / Q9DBG1* / CYP27A1* / Sterol 26-hydroxylase, mitochondrial * / cytochrome P450 family 27 subfamily A member 1*ENSDARG0000006918621
si:ch211-113j14.1ENSDARG0000007376421
A8WGA0 / cyp27c1 / cytochrome P450, family 27, subfamily C, polypeptide 1 / Q4G0S4* / cytochrome P450 family 27 subfamily C member 1*ENSDARG0000009266020
zgc:136333 / CYP27A1 (1 of many) / Q02318* / Q9DBG1* / CYP27A1* / Sterol 26-hydroxylase, mitochondrial * / cytochrome P450 family 27 subfamily A member 1*ENSDARG0000008801320
cyp27a7 / cytochrome P450, family 27, subfamily A, polypeptide 7 / Q02318* / Q9DBG1* / CYP27A1* / Sterol 26-hydroxylase, mitochondrial * / cytochrome P450 family 27 subfamily A member 1*ENSDARG0000003380220
cyp27a1.4 / cytochrome P450, family 27, subfamily A, polypeptide 1, gene 4 / Q02318* / Q9DBG1* / CYP27A1* / Sterol 26-hydroxylase, mitochondrial * / cytochrome P450 family 27 subfamily A member 1*ENSDARG0000005515920
cyp27b1 / cytochrome P450, family 27, subfamily B, polypeptide 1 / O15528* / O35084* / cytochrome P450 family 27 subfamily B member 1* / 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial *ENSDARG0000004501520
cyp11a2 / cytochrome P450, family 11, subfamily A, polypeptide 2 / Q9QZ82* / P05108* / CYP11A1* / cytochrome P450 family 11 subfamily A member 1* / Cholesterol side-chain cleavage enzyme, m...ENSDARG0000009269619
si:dkey-91i10.3ENSDARG0000005726219
cyp11c1 / cytochrome P450, family 11, subfamily C, polypeptide 1 / P19099* / P15538* / CYP11B1* / CYP11B2* / cytochrome P450 family 11 subfamily B member 2* / cytochrome P450 family 11 subf...ENSDARG0000004201418


Protein motifs (from Interpro)
Interpro ID Name
 IPR001128  Cytochrome P450
 IPR002401  Cytochrome P450, E-class, group I


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0055114 oxidation-reduction process IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0020037 heme binding IEA


Pathways (from Reactome)
Pathway description
Synthesis of bile acids and bile salts via 24-hydroxycholesterol
Endogenous sterols


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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