ENSDARG00000005926


Danio rerio

Features
Gene ID: ENSDARG00000005926
  
Biological name :ak2
  
Synonyms : adenylate kinase 2 / ak2 / Q1L8L9
  
Possible biological names infered from orthology : Adenylate kinase 2, mitochondrial / P54819 / Q9WTP6
  
Species: Danio rerio
  
Chr. number: 19
Strand: -1
Band:
Gene start: 35418683
Gene end: 35428914
  
Corresponding Affymetrix probe sets: Dr.25759.2.A1_a_at (Zebrafish Array)   NM_212596_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000131617
Ensembl peptide - ENSDARP00000010686
NCBI entrez gene - 321793     See in Manteia.
RefSeq - NM_212596
RefSeq Peptide - NP_997761
swissprot - A0A0F6PK88
swissprot - Q1L8L9
ZFIN ID - ZDB-GENE-030131-512
Ensembl - ENSDARG00000005926
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AK2ENSGALG00000003597Gallus gallus
 AK2ENSG00000004455Homo sapiens
 Ak2ENSMUSG00000028792Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ak8 / adenylate kinase 8 / Q32M07* / Q96MA6*ENSDARG0000003096126


Protein motifs (from Interpro)
Interpro ID Name
 IPR000850  Adenylate kinase/UMP-CMP kinase
 IPR006259  Adenylate kinase subfamily
 IPR007862  Adenylate kinase, active site lid domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR028587  Adenylate kinase 2
 IPR033690  Adenylate kinase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002244 hematopoietic progenitor cell differentiation IMP
 biological_processGO:0002521 leukocyte differentiation IMP
 biological_processGO:0006139 nucleobase-containing compound metabolic process IEA
 biological_processGO:0006172 ADP biosynthetic process IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0046033 AMP metabolic process IEA
 biological_processGO:0046034 ATP metabolic process IEA
 biological_processGO:0046939 nucleotide phosphorylation IEA
 biological_processGO:0060218 hematopoietic stem cell differentiation IMP
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005758 mitochondrial intermembrane space IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004017 adenylate kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016776 phosphotransferase activity, phosphate group as acceptor IEA
 molecular_functionGO:0019205 nucleobase-containing compound kinase activity IEA


Pathways (from Reactome)
Pathway description
Interconversion of nucleotide di- and triphosphates


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000033 intermediate cell mass of mesoderm intermediate cell mass of mesoderm apoptotic process increased process quality , abnormal
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 ZFA:0000094 blood island blood island apoptotic process increased process quality , abnormal
Show

 ZFA:0005023 hematopoietic system hematopoietic system apoptotic process increased process quality , abnormal
Show

 ZFA:0009048 granulocyte granulocyte decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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