ENSDARG00000006370


Danio rerio

Features
Gene ID: ENSDARG00000006370
  
Biological name :atp6v1h
  
Synonyms : atp6v1h / ATPase H+ transporting V1 subunit H
  
Possible biological names infered from orthology : Q8BVE3 / Q9UI12 / V-type proton ATPase subunit H
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 30786773
Gene end: 30846927
  
Corresponding Affymetrix probe sets: Dr.7421.1.S1_at (Zebrafish Array)   NM_173270_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000146642
Ensembl peptide - ENSDARP00000024886
Ensembl peptide - ENSDARP00000113453
Ensembl peptide - ENSDARP00000124373
NCBI entrez gene - 286779     See in Manteia.
RefSeq - NM_173270
RefSeq - NM_001291708
RefSeq Peptide - NP_001278637
RefSeq Peptide - NP_775377
swissprot - F8W3K9
swissprot - B0R0V8
swissprot - Q6PC35
ZFIN ID - ZDB-GENE-021219-2
Ensembl - ENSDARG00000006370
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ATP6V1HENSGALG00000013621Gallus gallus
 Q9UI12ENSG00000047249Homo sapiens
 Q8BVE3ENSMUSG00000033793Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004908  ATPase, V1 complex, subunit H
 IPR011987  ATPase, V1 complex, subunit H, C-terminal
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007035 vacuolar acidification IBA
 biological_processGO:0015991 ATP hydrolysis coupled proton transport IEA
 biological_processGO:0030282 bone mineralization IMP
 biological_processGO:0043473 pigmentation IMP
 biological_processGO:0048069 eye pigmentation IMP
 biological_processGO:0060041 retina development in camera-type eye IMP
 biological_processGO:0060348 bone development IMP
 biological_processGO:0061075 positive regulation of neural retina development IMP
 cellular_componentGO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain IBA
 cellular_componentGO:0005765 lysosomal membrane IBA
 molecular_functionGO:0046961 proton-transporting ATPase activity, rotational mechanism IBA


Pathways (from Reactome)
Pathway description
ROS, RNS production in phagocytes
Insulin receptor recycling
Transferrin endocytosis and recycling
Ion channel transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain necrotic , abnormal
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 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000076 swim bladder swim bladder uninflated , abnormal
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 ZFA:0000107 eye eye color , abnormal
eye decreased size , abnormal
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 ZFA:0000112 gut gut hypoplastic , abnormal
gut decreased size , abnormal
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 ZFA:0000123 liver liver hypoplastic , abnormal
liver decreased size , abnormal
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 ZFA:0000126 centrum centrum hollow , abnormal
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 ZFA:0000144 retinal pigmented epithelium retinal pigmented epithelium malformed , abnormal
retinal pigmented epithelium physical object quality , abnormal
retinal pigmented epithelium translucent , abnormal
retinal pigmented epithelium quality , abnormal
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 ZFA:0000396 nervous system nervous system quality , abnormal
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 ZFA:0000737 cranium cranium increased amount , abnormal
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 ZFA:0001094 whole organism whole organism low saturation , abnormal
whole organism decreased pigmentation , abnormal
whole organism increased amount , abnormal
whole organism dead , abnormal
whole organism decreased life span , abnormal
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 ZFA:0001114 head head decreased size , abnormal
head decreased pigmentation , abnormal
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 ZFA:0001115 trunk trunk curved , abnormal
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 ZFA:0001189 vertebra vertebra morphology , abnormal
vertebra decreased size , abnormal
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 ZFA:0005220 larval melanophore stripe larval melanophore stripe melanocyte translucent , abnormal
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 ZFA:0009090 pigment cell pigment cell decreased amount , abnormal
pigment cell quality , abnormal
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 ZFA:0009091 melanocyte melanocyte decreased size , abnormal
melanocyte increased size , abnormal
melanocyte malformed , abnormal
melanocyte translucent , abnormal
melanocyte absent , abnormal
melanocyte melanosome circular , abnormal
melanocyte melanosome decreased size , abnormal
melanocyte melanosome decreased pigmentation , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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