ENSDARG00000008840


Danio rerio

Features
Gene ID: ENSDARG00000008840
  
Biological name :hmbsa
  
Synonyms : hmbsa / hydroxymethylbilane synthase a
  
Possible biological names infered from orthology : HMBS / hydroxymethylbilane synthase / P08397 / P22907 / Porphobilinogen deaminase
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 30518036
Gene end: 30534426
  
Corresponding Affymetrix probe sets: Dr.3338.1.S1_at (Zebrafish Array)   NM_201154_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000023322
Ensembl peptide - ENSDARP00000136190
Ensembl peptide - ENSDARP00000112737
NCBI entrez gene - 394129     See in Manteia.
RefSeq - NM_201154
RefSeq - XM_005171816
RefSeq Peptide - NP_957448
swissprot - A0A0R4IQ55
swissprot - A2BFN7
swissprot - A2BFN6
ZFIN ID - ZDB-GENE-040426-1375
Ensembl - ENSDARG00000008840
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HMBSENSGALG00000042939Gallus gallus
 HMBSENSG00000256269Homo sapiens
 HmbsENSMUSG00000032126Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
hmbsb / hydroxymethylbilane synthase, b / HMBS* / P08397* / P22907* / Porphobilinogen deaminase * / hydroxymethylbilane synthase*ENSDARG0000005599175


Protein motifs (from Interpro)
Interpro ID Name
 IPR000860  Porphobilinogen deaminase
 IPR022417  Porphobilinogen deaminase, N-terminal
 IPR022418  Porphobilinogen deaminase, C-terminal
 IPR022419  Porphobilinogen deaminase, dipyrromethane cofactor binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006783 heme biosynthetic process IBA
 biological_processGO:0018160 peptidyl-pyrromethane cofactor linkage IEA
 biological_processGO:0033014 tetrapyrrole biosynthetic process IEA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0004418 hydroxymethylbilane synthase activity IEA


Pathways (from Reactome)
Pathway description
Heme biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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