ENSDARG00000009953


Danio rerio

Features
Gene ID: ENSDARG00000009953
  
Biological name :med14
  
Synonyms : med14 / mediator complex subunit 14
  
Possible biological names infered from orthology : A2ABV5 / Mediator of RNA polymerase II transcription subunit 14 / O60244
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 34397516
Gene end: 34428152
  
Corresponding Affymetrix probe sets: Dr.8754.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000123079
Ensembl peptide - ENSDARP00000152971
Ensembl peptide - ENSDARP00000010465
NCBI entrez gene - 336923     See in Manteia.
RefSeq - XM_005167822
swissprot - E9QDB5
swissprot - F1R9C9
ZFIN ID - ZDB-GENE-030131-8867
Ensembl - ENSDARG00000009953
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MED14ENSGALG00000016238Gallus gallus
 MED14ENSG00000180182Homo sapiens
 Med14ENSMUSG00000064127Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR013947  Mediator complex, subunit Med14


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007420 brain development IMP
 biological_processGO:0019827 stem cell population maintenance IMP
 biological_processGO:0021591 ventricular system development IMP
 biological_processGO:0030518 intracellular steroid hormone receptor signaling pathway IBA
 biological_processGO:0048514 blood vessel morphogenesis IMP
 cellular_componentGO:0016592 mediator complex IEA
 cellular_componentGO:0070847 core mediator complex IBA


Pathways (from Reactome)
Pathway description
Generic Transcription Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000007 blood blood has fewer parts of type nucleate erythrocyte , abnormal
Show

 ZFA:0000008 brain brain quality , abnormal
Show

 ZFA:0000014 dorsal aorta dorsal aorta collapsed , abnormal
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 ZFA:0000029 hindbrain hindbrain quality , abnormal
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 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000084 yolk yolk quality , abnormal
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 ZFA:0000108 fin fin quality , abnormal
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 ZFA:0000110 fourth ventricle fourth ventricle decreased size , abnormal
fourth ventricle decreased diameter , abnormal
Show

 ZFA:0000112 gut gut quality , abnormal
gut hypoplastic , abnormal
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 ZFA:0000114 heart heart quality , abnormal
heart edematous , abnormal
heart has fewer parts of type cardiac muscle cell , abnormal
heart morphology , abnormal
Show

 ZFA:0000123 liver liver quality , abnormal
liver hypoplastic , abnormal
Show

 ZFA:0000152 retina retina has fewer parts of type somatic stem cell , abnormal
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 ZFA:0000159 tectal ventricle tectal ventricle decreased size , abnormal
Show

 ZFA:0000217 inner ear inner ear lacks all parts of type semicircular canal , abnormal
inner ear morphology , abnormal
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 ZFA:0000360 heart tube heart tube malformed , abnormal
Show

 ZFA:0000477 posterior cardinal vein posterior cardinal vein collapsed , abnormal
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 ZFA:0001056 myotome myotome skeletal muscle cell malformed , abnormal
Show

 ZFA:0001094 whole organism whole organism lethal (sensu genetics) , abnormal
Show

 ZFA:0001114 head head circular , abnormal
head decreased size , abnormal
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 ZFA:0001161 pectoral fin pectoral fin decreased length , abnormal
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 ZFA:0001205 Meckel s cartilage Meckels cartilage absent , abnormal
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 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton quality , abnormal
mandibular arch skeleton morphology , abnormal
Show

 ZFA:0001259 forebrain ventricle forebrain ventricle decreased size , abnormal
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 ZFA:0001261 ventricular system ventricular system decreased size , abnormal
ventricular system collapsed , abnormal
Show

 ZFA:0001306 pharyngeal arch pharyngeal arch decreased amount , abnormal
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 ZFA:0001399 palatoquadrate cartilage palatoquadrate cartilage decreased size , abnormal
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 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage absent , abnormal
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 ZFA:0001405 ethmoid cartilage ethmoid cartilage absent , abnormal
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 ZFA:0001423 parachordal cartilage parachordal cartilage absent , abnormal
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 ZFA:0001439 anatomical system anatomical system quality , abnormal
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 ZFA:0001517 ceratobranchial 2 cartilage ceratobranchial 2 cartilage absent , abnormal
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 ZFA:0001518 ceratobranchial 3 cartilage ceratobranchial 3 cartilage absent , abnormal
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 ZFA:0001519 ceratobranchial 4 cartilage ceratobranchial 4 cartilage absent , abnormal
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 ZFA:0001520 ceratobranchial 1 cartilage ceratobranchial 1 cartilage absent , abnormal
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 ZFA:0001521 ceratobranchial 5 cartilage ceratobranchial 5 cartilage absent , abnormal
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 ZFA:0009036 blood vessel endothelial cell blood vessel endothelial cell decreased amount , abnormal
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 ZFA:0009091 melanocyte melanocyte morphology , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr