ENSDARG00000012030


Danio rerio

Features
Gene ID: ENSDARG00000012030
  
Biological name :dnaaf1
  
Synonyms : dnaaf1 / dynein, axonemal, assembly factor 1
  
Possible biological names infered from orthology : Dynein assembly factor 1, axonemal / Q8NEP3 / Q9D2H9
  
Species: Danio rerio
  
Chr. number: 7
Strand: 1
Band:
Gene start: 29012033
Gene end: 29017892
  
Corresponding Affymetrix probe sets: Dr.18527.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000115728
Ensembl peptide - ENSDARP00000142875
Ensembl peptide - ENSDARP00000142666
NCBI entrez gene - 386722     See in Manteia.
swissprot - A0A1D5NSQ8
swissprot - A0A1D5NS57
swissprot - F1Q654
ZFIN ID - ZDB-GENE-031114-4
Ensembl - ENSDARG00000012030
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DNAAF1ENSGALG00000003258Gallus gallus
 DNAAF1ENSG00000154099Homo sapiens
 Dnaaf1ENSMUSG00000031831Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
lrguk / leucine-rich repeats and guanylate kinase domain containing / Q96M69* / Q9D5S7* / Leucine-rich repeat and guanylate kinase domain-containing protein *ENSDARG0000006969812
drc3 / dynein regulatory complex subunit 3 / Q9H069*ENSDARG0000004130012
ppp1r7 / Q32PL1 / protein phosphatase 1, regulatory (inhibitor) subunit 7 / Q3UM45* / Q15435* / protein phosphatase 1 regulatory subunit 7*ENSDARG000000097409
lrrc23 / leucine rich repeat containing 23 / O35125* / Q53EV4* / Leucine-rich repeat-containing protein 23 *ENSDARG000000061746
lrrc9 / leucine rich repeat containing 9ENSDARG000000543523


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR027734  Dynein assembly factor 1, axonemal
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0044458 motile cilium assembly IEA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0042995 cell projection IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000001 Kupffer s vesicle Kupffers vesicle spatial pattern , abnormal
Kupffers vesicle cilium spatial pattern , abnormal
Kupffers vesicle cilium immobile , abnormal
Show

 ZFA:0000107 eye eye morphology , abnormal
Show

 ZFA:0000114 heart heart morphology , abnormal
Show

 ZFA:0000135 notochord notochord increased width , abnormal
notochord kinked , abnormal
Show

 ZFA:0000150 pronephric duct pronephric duct brush border decreased size , abnormal
pronephric duct dilated , abnormal
pronephric duct brush border irregular spatial pattern , abnormal
pronephric duct cilium disorganized , abnormal
Show

 ZFA:0000151 pronephros pronephros cystic , abnormal
pronephros cilium immobile , abnormal
pronephros axoneme structure , abnormal
Show

 ZFA:0000155 somite somite decreased thickness , abnormal
somite elongated , abnormal
Show

 ZFA:0000598 testis testis hyperplastic , abnormal
testis germ cell tumor increased amount , abnormal
testis germ cell tumor proliferative , abnormal
testis seminoma present , abnormal
testis spermatogonium increased amount , abnormal
testis germ cell tumor present , abnormal
testis sperm decreased amount , abnormal
Show

 ZFA:0001094 whole organism whole organism lethal (sensu genetics) , abnormal
whole organism edematous , abnormal
whole organism increased curvature , abnormal
whole organism shape , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
Show

 ZFA:0001115 trunk trunk curved ventral , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved ventral , abnormal
post-vent region curved , abnormal
Show

 ZFA:0001469 lateral line lateral line kinocilium decreased length , abnormal
lateral line kinocilium decreased amount , abnormal
Show

 ZFA:0001557 pronephric glomerulus pronephric glomerulus increased size , abnormal
Show

 ZFA:0001558 pronephric tubule pronephric tubule dilated , abnormal
pronephric tubule increased diameter , abnormal
pronephric tubule cystic , abnormal
pronephric tubule morphology , abnormal
Show

 ZFA:0001617 otolith otolith morphology , abnormal
Show

 ZFA:0009006 sperm sperm decreased amount , abnormal
Show

 ZFA:0009007 spermatogonium spermatogonium increased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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