ENSDARG00000013837


Danio rerio

Features
Gene ID: ENSDARG00000013837
  
Biological name :spo11
  
Synonyms : spo11 / SPO11 meiotic protein covalently bound to DSB
  
Possible biological names infered from orthology : Meiotic recombination protein SPO11 / Q9WTK8 / Q9Y5K1 / SPO11, initiator of meiotic double stranded breaks
  
Species: Danio rerio
  
Chr. number: 23
Strand: 1
Band:
Gene start: 6544453
Gene end: 6574123
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000002837
NCBI entrez gene - 402982     See in Manteia.
RefSeq - NM_205682
RefSeq Peptide - NP_991245
swissprot - F1QVE0
ZFIN ID - ZDB-GENE-040426-1900
Ensembl - ENSDARG00000013837
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SPO11ENSGALG00000031768Gallus gallus
 SPO11ENSG00000054796Homo sapiens
 Spo11ENSMUSG00000005883Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002815  Spo11/DNA topoisomerase VI subunit A
 IPR011991  ArsR-like helix-turn-helix domain
 IPR013048  Meiotic recombination, Spo11
 IPR013049  Spo11/DNA topoisomerase VI, subunit A, N-terminal
 IPR034136  Topoisomerase 6 subunit A/Spo11, TOPRIM domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000706 meiotic DNA double-strand break processing IBA
 biological_processGO:0000737 DNA catabolic process, endonucleolytic IEA
 biological_processGO:0006259 DNA metabolic process IEA
 biological_processGO:0007131 reciprocal meiotic recombination IBA
 biological_processGO:0042138 meiotic DNA double-strand break formation IBA
 cellular_componentGO:0000228 nuclear chromosome IBA
 cellular_componentGO:0005694 chromosome IEA
 molecular_functionGO:0003677 DNA binding IBA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016889 endodeoxyribonuclease activity, producing 3"-phosphomonoesters IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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