ENSDARG00000016904


Danio rerio

Features
Gene ID: ENSDARG00000016904
  
Biological name :bckdk
  
Synonyms : bckdk / branched chain ketoacid dehydrogenase kinase
  
Possible biological names infered from orthology : [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial / O14874 / O55028
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 61508418
Gene end: 61554010
  
Corresponding Affymetrix probe sets: Dr.25159.1.S1_at (Zebrafish Array)   NM_213060_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000021993
NCBI entrez gene - 282677     See in Manteia.
RefSeq - NM_213060
RefSeq Peptide - NP_998225
swissprot - B0R159
ZFIN ID - ZDB-GENE-021204-1
Ensembl - ENSDARG00000016904
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BCKDKENSG00000103507Homo sapiens
 BckdkENSMUSG00000030802Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pdk2a / pyruvate dehydrogenase kinase, isozyme 2a / PDK2* / Q9JK42* / Q15119* / pyruvate dehydrogenase kinase 2* / [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial *ENSDARG0000002087626
pdk1 / pyruvate dehydrogenase kinase, isozyme 1 / Q15118* / Q8BFP9* / pyruvate dehydrogenase kinase 1* / [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial *ENSDARG0000001312826
pdk3a / pyruvate dehydrogenase kinase, isozyme 3a / PDK3* / Q922H2* / Q15120* / pyruvate dehydrogenase kinase 3* / pyruvate dehydrogenase kinase, isoenzyme 3*ENSDARG0000001452725
pdk2b / pyruvate dehydrogenase kinase, isozyme 2b / PDK2* / Q9JK42* / Q15119* / pyruvate dehydrogenase kinase 2* / [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial *ENSDARG0000005905425
pdk4 / pyruvate dehydrogenase kinase, isozyme 4 / O70571* / Q16654* / pyruvate dehydrogenase kinase 4* / pyruvate dehydrogenase kinase, isoenzyme 4*ENSDARG0000005484824
pdk3b / pyruvate dehydrogenase kinase, isozyme 3b / PDK3* / Q922H2* / Q15120* / pyruvate dehydrogenase kinase 3* / pyruvate dehydrogenase kinase, isoenzyme 3*ENSDARG0000009979110


Protein motifs (from Interpro)
Interpro ID Name
 IPR003594  Histidine kinase/HSP90-like ATPase
 IPR004358  Signal transduction histidine kinase-related protein, C-terminal
 IPR005467  Histidine kinase domain
 IPR018955  Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016310 phosphorylation IEA
 molecular_functionGO:0016772 transferase activity, transferring phosphorus-containing groups IEA


Pathways (from Reactome)
Pathway description
Branched-chain amino acid catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000040555 bckdha / branched chain keto acid dehydrogenase E1, alpha polypeptide / P12694* / AC011462.1* / branched chain ketoacid dehydrogenase E1, alpha polypeptide*  / reaction
 ENSDARG00000008785 dldh / dihydrolipoamide dehydrogenase / DLD* / O08749* / P09622* / Dihydrolipoyl dehydrogenase, mitochondrial *  / reaction






 

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