ENSDARG00000021022


Danio rerio

Features
Gene ID: ENSDARG00000021022
  
Biological name :ift57
  
Synonyms : ift57 / intraflagellar transport 57 homolog (Chlamydomonas) / Q6IVW0
  
Possible biological names infered from orthology : Intraflagellar transport / intraflagellar transport 57 / Q8BXG3 / Q9NWB7
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 42200390
Gene end: 42210526
  
Corresponding Affymetrix probe sets: Dr.15138.1.S1_at (Zebrafish Array)   NM_001001832_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000013774
NCBI entrez gene - 414929     See in Manteia.
RefSeq - NM_001001832
RefSeq Peptide - NP_001001832
swissprot - Q6IVW0
ZFIN ID - ZDB-GENE-040614-1
Ensembl - ENSDARG00000021022
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IFT57ENSGALG00000015356Gallus gallus
 IFT57ENSG00000114446Homo sapiens
 Ift57ENSMUSG00000032965Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR019530  Intra-flagellar transport protein 57


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003351 epithelial cilium movement IMP
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007368 determination of left/right symmetry IGI
 biological_processGO:0032006 regulation of TOR signaling IMP
 biological_processGO:0042073 intraciliary transport IMP
 biological_processGO:0042462 eye photoreceptor cell development IMP
 biological_processGO:0045494 photoreceptor cell maintenance IMP
 biological_processGO:0060271 cilium assembly IMP
 biological_processGO:1905515 non-motile cilium assembly IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IBA
 cellular_componentGO:0005813 centrosome IBA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0030992 intraciliary transport particle B ISS
 cellular_componentGO:0036064 ciliary basal body ISS
 cellular_componentGO:0042995 cell projection IEA


Pathways (from Reactome)
Pathway description
Hedgehog off state
Intraflagellar transport
Hedgehog on state


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000051 otic vesicle otic vesicle decreased size , abnormal
otic vesicle cilium decreased length , abnormal
otic vesicle cilium decreased amount , abnormal
Show

 ZFA:0000107 eye eye quality , abnormal
eye decreased size , abnormal
Show

 ZFA:0000143 retinal photoreceptor layer retinal photoreceptor layer quality , abnormal
retinal photoreceptor layer eye photoreceptor cell apoptotic , abnormal
Show

 ZFA:0000151 pronephros pronephros quality , abnormal
pronephros cystic , abnormal
Show

 ZFA:0000152 retina retina photoreceptor outer segment decreased length , abnormal
Show

 ZFA:0000360 heart tube heart tube position , abnormal
Show

 ZFA:0000529 kidney kidney cystic , abnormal
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 ZFA:0001094 whole organism whole organism shape , abnormal
Show

 ZFA:0001115 trunk trunk curved , abnormal
trunk undulate , abnormal
trunk curved ventral , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved ventral , abnormal
Show

 ZFA:0001135 neural tube neural tube axoneme absent , abnormal
Show

 ZFA:0001464 retinal outer nuclear layer retinal outer nuclear layer perforate , abnormal
retinal outer nuclear layer eye photoreceptor cell apoptotic , abnormal
Show

 ZFA:0009154 eye photoreceptor cell eye photoreceptor cell vesicle membrane present , abnormal
eye photoreceptor cell photoreceptor outer segment decreased length , abnormal
eye photoreceptor cell photoreceptor outer segment disheveled , abnormal
Show

 ZFA:0009222 blue sensitive photoreceptor cell blue sensitive photoreceptor cell morphology , abnormal
Show

 ZFA:0009262 retinal cone cell retinal cone cell decreased length , abnormal
retinal cone cell morphology , abnormal
Show

 ZFA:0009275 retinal rod cell retinal rod cell morphology , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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