ENSDARG00000024904


Danio rerio

Features
Gene ID: ENSDARG00000024904
  
Biological name :stil
  
Synonyms : Q8JGS1 / scl/tal1 interrupting locus / stil
  
Possible biological names infered from orthology : Q15468 / SCL-interrupting locus protein homolog isoform 5 / STIL, centriolar assembly protein
  
Species: Danio rerio
  
Chr. number: 22
Strand: 1
Band:
Gene start: 15959844
Gene end: 15973184
  
Corresponding Affymetrix probe sets: Dr.11575.1.S1_at (Zebrafish Array)   NM_173244_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000037419
Ensembl peptide - ENSDARP00000144848
Ensembl peptide - ENSDARP00000146321
NCBI entrez gene - 192317     See in Manteia.
RefSeq - NM_173244
RefSeq Peptide - NP_775351
swissprot - Q8JGS1
ZFIN ID - ZDB-GENE-020419-39
Ensembl - ENSDARG00000024904
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 STILENSGALG00000010478Gallus gallus
 STILENSG00000123473Homo sapiens
 StilENSMUSG00000028718Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR026123  SCL-interrupting locus protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007052 mitotic spindle organization IMP
 biological_processGO:0007224 smoothened signaling pathway IGI
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0010171 body morphogenesis IMP
 biological_processGO:0046599 regulation of centriole replication ISS
 biological_processGO:0051225 spindle assembly IMP
 biological_processGO:0070050 neuron cellular homeostasis IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005814 centriole ISS
 cellular_componentGO:0005856 cytoskeleton IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain necrotic , abnormal
brain decreased size , abnormal
brain degeneration , abnormal
brain cell death increased occurrence , abnormal
Show

 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
Show

 ZFA:0000035 lens lens protruding out of eye , abnormal
Show

 ZFA:0000046 retinal neural layer retinal neural layer disorganized , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000075 spinal cord spinal cord mitotic cell cycle increased occurrence , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
eye degeneration , abnormal
eye cell death increased occurrence , abnormal
Show

 ZFA:0000112 gut gut hypoplastic , abnormal
Show

 ZFA:0000114 heart heart edematous , abnormal
heart quality , abnormal
Show

 ZFA:0000119 retinal inner nuclear layer retinal inner nuclear layer hollow , abnormal
retinal inner nuclear layer cell swollen , abnormal
Show

 ZFA:0000123 liver liver hypoplastic , abnormal
Show

 ZFA:0000152 retina retina decreased size , abnormal
retina disorganized , abnormal
retina has fewer parts of type retina cell, abnormal
retina mitotic cell cycle increased occurrence , abnormal
retina apoptotic process increased occurrence , abnormal
retina mitotic M phase increased duration , abnormal
retina mitotic prometaphase arrested , abnormal
retina mitotic prometaphase increased duration , abnormal
retina mitotic cell cycle arrested , abnormal
retina mitotic cell cycle increased duration , abnormal
retina M phase increased duration , abnormal
retina cell division increased duration , abnormal
retina dopaminergic neuron decreased amount , abnormal
retina lacks parts or has fewer parts of type cell centrosome, abnormal
Show

 ZFA:0000396 nervous system nervous system quality , abnormal
Show

 ZFA:0001058 caudal fin caudal fin curved , abnormal
Show

 ZFA:0001094 whole organism whole organism lethal (sensu genetics) , abnormal
whole organism curved dorsal , abnormal
whole organism decreased size , abnormal
whole organism bent , abnormal
whole organism dead , abnormal
Show

 ZFA:0001114 head head neuron apoptotic , abnormal
head decreased size , abnormal
Show

 ZFA:0001115 trunk trunk curved dorsal , abnormal
trunk curved ventral , abnormal
trunk sigmoid , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved , abnormal
Show

 ZFA:0001329 retinal inner plexiform layer retinal inner plexiform layer transmission of nerve impulse process quality , abnormal
Show

 ZFA:0001356 terminal nerve terminal nerve neuron projection disorganized , abnormal
terminal nerve neuron projection decreased branchiness , abnormal
Show

 ZFA:0007009 nerve nerve degeneration , abnormal
Show

 ZFA:0009000 cell cell gamma-tubulin complex mislocalised , abnormal
cell spindle disorganized , abnormal
cell spindle pole centrosome absent , abnormal
Show

 ZFA:0009301 dopaminergic neuron dopaminergic neuron degeneration , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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