ENSDARG00000031388


Danio rerio

Features
Gene ID: ENSDARG00000031388
  
Biological name :dctn2
  
Synonyms : dctn2 / dynactin 2 (p50)
  
Possible biological names infered from orthology : dynactin subunit 2 / Q13561 / Q99KJ8
  
Species: Danio rerio
  
Chr. number: 6
Strand: 1
Band:
Gene start: 58832155
Gene end: 58867662
  
Corresponding Affymetrix probe sets: Dr.2827.1.S1_at (Zebrafish Array)   NM_201166_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000042594
Ensembl peptide - ENSDARP00000121669
NCBI entrez gene - 394141     See in Manteia.
RefSeq - NM_201166
RefSeq - XM_005166169
RefSeq Peptide - NP_957460
swissprot - F1QA97
swissprot - E7FB97
swissprot - E9QF92
ZFIN ID - ZDB-GENE-040426-1279
Ensembl - ENSDARG00000031388
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DCTN2ENSG00000175203Homo sapiens
 Dctn2ENSMUSG00000025410Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR028133  Dynamitin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007017 microtubule-based process IEA
 cellular_componentGO:0005869 dynactin complex IEA


Pathways (from Reactome)
Pathway description
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000143 retinal photoreceptor layer retinal photoreceptor layer aplastic , abnormal
Show

 ZFA:0000281 hair cell posterior macula hair cell posterior macula decreased amount , abnormal
Show

 ZFA:0001094 whole organism whole organism lethal (sensu genetics) , abnormal
Show

 ZFA:0001466 photoreceptor outer segment layer photoreceptor outer segment layer photoreceptor outer segment deformed , abnormal
photoreceptor outer segment layer photoreceptor outer segment decreased amount , abnormal
Show

 ZFA:0009127 photoreceptor cell photoreceptor cell morphology , abnormal
photoreceptor cell decreased amount , abnormal
Show

 ZFA:0009280 Muller cell Muller cell decreased amount , abnormal
Muller cell perikaryon mislocalised , abnormal
Muller cell apical-basal polarity , abnormal
Show

 ZFA:0009367 neuromast hair cell neuromast hair cell decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr