ENSDARG00000032344


Danio rerio

Features
Gene ID: ENSDARG00000032344
  
Biological name :pde4a
  
Synonyms : pde4a / phosphodiesterase 4A, cAMP-specific
  
Possible biological names infered from orthology : O89084 / P27815 / phosphodiesterase 4A
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 46628885
Gene end: 46754730
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000024572
Ensembl peptide - ENSDARP00000153858
NCBI entrez gene - 572061     See in Manteia.
RefSeq - XM_009299744
swissprot - E7FAS0
ZFIN ID - ZDB-GENE-131125-7
Ensembl - ENSDARG00000032344
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PDE4AENSG00000065989Homo sapiens
 Pde4aENSMUSG00000032177Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pde4ba / phosphodiesterase 4B, cAMP-specific a / PDE4B* / Q07343* / phosphodiesterase 4B* / phosphodiesterase 4B, cAMP specific*ENSDARG0000003286863
pde4d / phosphodiesterase 4D, cAMP-specific / Q01063* / Q08499* / phosphodiesterase 4D* / cAMP-specific 3,5-cyclic phosphodiesterase 4D *ENSDARG0000003276162
pde4bb / phosphodiesterase 4B, cAMP-specific b / PDE4B* / Q07343* / phosphodiesterase 4B* / phosphodiesterase 4B, cAMP specific*ENSDARG0000007423359
pde4cb / phosphodiesterase 4C, cAMP-specific b / PDE4C* / Q3UEI1* / Q08493* / AC008397.2* / phosphodiesterase 4C* / cAMP-specific 3,5-cyclic phosphodiesterase 4C *ENSDARG0000000241159
pde4ca / phosphodiesterase 4C, cAMP-specific a / PDE4C* / Q3UEI1* / Q08493* / AC008397.2* / phosphodiesterase 4C* / cAMP-specific 3,5-cyclic phosphodiesterase 4C *ENSDARG0000001322157
pde1a / phosphodiesterase 1A, calmodulin-dependent / P54750* / phosphodiesterase 1A*ENSDARG0000006087520
CABZ01067973.1 / PDE1C* / Q14123* / phosphodiesterase 1C*ENSDARG0000009039819
pde8b / phosphodiesterase 8B / O95263* / AC022414.1* / high affinity cAMP-specific and IBMX-insensitive 3,5-cyclic phosphodiesterase 8B isoform 11 *ENSDARG0000006370619
pde7a / phosphodiesterase 7A / P70453* / Q13946* / High affinity cAMP-specific 3,5-cyclic phosphodiesterase 7A *ENSDARG0000004530518
pde8a / phosphodiesterase 8A / O60658*ENSDARG0000008794114


Protein motifs (from Interpro)
Interpro ID Name
 IPR002073  3"5"-cyclic nucleotide phosphodiesterase, catalytic domain
 IPR003607  HD/PDEase domain
 IPR023088  3"5"-cyclic nucleotide phosphodiesterase
 IPR023174  3"5"-cyclic nucleotide phosphodiesterase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 molecular_functionGO:0004114 3",5"-cyclic-nucleotide phosphodiesterase activity IEA
 molecular_functionGO:0008081 phosphoric diester hydrolase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
DARPP-32 events
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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