ENSDARG00000034396


Danio rerio

Features
Gene ID: ENSDARG00000034396
  
Biological name :mars
  
Synonyms : mars / methionyl-tRNA synthetase
  
Possible biological names infered from orthology : Methionine--tRNA ligase, cytoplasmic / P56192 / Q68FL6
  
Species: Danio rerio
  
Chr. number: 6
Strand: -1
Band:
Gene start: 58921240
Gene end: 58975019
  
Corresponding Affymetrix probe sets: Dr.21303.1.A1_x_at (Zebrafish Array)   Dr.6373.1.S1_at (Zebrafish Array)   NM_200076_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000123109
Ensembl peptide - ENSDARP00000122981
NCBI entrez gene - 338183     See in Manteia.
RefSeq - NM_200076
RefSeq Peptide - NP_956370
swissprot - F1QVW1
swissprot - F1QFL1
ZFIN ID - ZDB-GENE-030219-83
Ensembl - ENSDARG00000034396
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MARSENSG00000166986Homo sapiens
 MarsENSMUSG00000040354Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000738  WHEP-TRS domain
 IPR001412  Aminoacyl-tRNA synthetase, class I, conserved site
 IPR004045  Glutathione S-transferase, N-terminal
 IPR009068  S15/NS1, RNA-binding
 IPR009080  Aminoacyl-tRNA synthetase, class Ia, anticodon-binding
 IPR010987  Glutathione S-transferase, C-terminal-like
 IPR012336  Thioredoxin-like fold
 IPR014729  Rossmann-like alpha/beta/alpha sandwich fold
 IPR014758  Methionyl-tRNA synthetase
 IPR015413  Methionyl/Leucyl tRNA synthetase
 IPR023458  Methionine-tRNA ligase, type 1
 IPR029038  Methionyl-tRNA synthetase, Zn-domain
 IPR033911  Methioninyl-tRNA synthetase core domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IEA
 biological_processGO:0006418 tRNA aminoacylation for protein translation IBA
 biological_processGO:0006431 methionyl-tRNA aminoacylation IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004812 aminoacyl-tRNA ligase activity IEA
 molecular_functionGO:0004825 methionine-tRNA ligase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016874 ligase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000112 gut gut hypoplastic , abnormal
gut quality , abnormal
Show

 ZFA:0000123 liver liver hypoplastic , abnormal
liver quality , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved , abnormal
Show

 ZFA:0001216 splanchnocranium splanchnocranium hypoplastic , abnormal
Show

 ZFA:0001306 pharyngeal arch pharyngeal arch hypoplastic , abnormal
Show

 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage malformed , abnormal
Show

 ZFA:0001439 anatomical system anatomical system quality , abnormal
Show

 ZFA:0001518 ceratobranchial 3 cartilage ceratobranchial 3 cartilage aplastic , abnormal
Show

 ZFA:0001519 ceratobranchial 4 cartilage ceratobranchial 4 cartilage aplastic , abnormal
Show

 ZFA:0001521 ceratobranchial 5 cartilage ceratobranchial 5 cartilage aplastic , abnormal
Show

 ZFA:0001580 neurocranium neurocranium malformed , abnormal
Show

 ZFA:0001611 pharyngeal arch 2 pharyngeal arch 2 hypoplastic , abnormal
Show

 ZFA:0001612 pharyngeal arch 1 pharyngeal arch 1 hypoplastic , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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