ENSDARG00000035563


Danio rerio

Features
Gene ID: ENSDARG00000035563
  
Biological name :znf703
  
Synonyms : Q90ZE2 / zinc finger protein 703 / znf703
  
Possible biological names infered from orthology : P0CL69 / Q9H7S9 / Zfp703
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 24329983
Gene end: 24333684
  
Corresponding Affymetrix probe sets: Dr.20027.1.S1_at (Zebrafish Array)   NM_131822_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000051552
NCBI entrez gene - 114429     See in Manteia.
RefSeq - NM_131822
RefSeq Peptide - NP_571897
swissprot - B2GT14
swissprot - Q90ZE2
ZFIN ID - ZDB-GENE-010717-1
Ensembl - ENSDARG00000035563
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ZNF703ENSGALG00000034229Gallus gallus
 Q9H7S9ENSG00000183779Homo sapiens
 P0CL69ENSMUSG00000085795Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6UFS5 / znf503 / zinc finger protein 503 / Q96F45* / Q7TMA2* / Zfp503*ENSDARG0000001849246


Protein motifs (from Interpro)
Interpro ID Name
 IPR013087  Zinc finger C2H2-type
 IPR022129  Transcriptional repressor NocA-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007368 determination of left/right symmetry IMP
 biological_processGO:0007420 brain development IMP
 biological_processGO:0017015 regulation of transforming growth factor beta receptor signaling pathway ISS
 biological_processGO:0030335 positive regulation of cell migration ISS
 biological_processGO:0030902 hindbrain development IGI
 biological_processGO:0031065 positive regulation of histone deacetylation IDA
 biological_processGO:0034111 negative regulation of homotypic cell-cell adhesion ISS
 biological_processGO:0034333 adherens junction assembly ISS
 biological_processGO:0045892 negative regulation of transcription, DNA-templated ISS
 biological_processGO:0048596 embryonic camera-type eye morphogenesis IMP
 biological_processGO:0060271 cilium assembly IMP
 biological_processGO:0060828 regulation of canonical Wnt signaling pathway ISS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0016363 nuclear matrix ISS
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding ISS
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000001 Kupffer s vesicle Kupffers vesicle decreased distribution , abnormal
Kupffers vesicle anatomical region absent , abnormal
Kupffers vesicle decreased size , abnormal
Kupffers vesicle lacks all parts of type Kupffers vesicle motile cilium, abnormal
Kupffers vesicle motile cilium absent , abnormal
Kupffers vesicle motile cilium decreased amount , abnormal
Show

 ZFA:0000008 brain brain hydrocephalic , abnormal
Show

 ZFA:0000022 floor plate floor plate motile cilium decreased amount , abnormal
Show

 ZFA:0000023 forerunner cell group forerunner cell group decreased distribution , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000107 eye eye malformed , abnormal
Show

 ZFA:0000121 lateral plate mesoderm lateral plate mesoderm right side mislocalised , abnormal
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 ZFA:0000144 retinal pigmented epithelium retinal pigmented epithelium split , abnormal
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 ZFA:0000151 pronephros pronephros cystic , abnormal
pronephros motile cilium decreased amount , abnormal
Show

 ZFA:0000152 retina retina malformed , abnormal
Show

 ZFA:0000360 heart tube heart tube mislocalised , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased amount , abnormal
whole organism anterior-posterior axis decreased length , abnormal
Show

 ZFA:0001117 post-vent region post-vent region increased curvature , abnormal
Show

 ZFA:0001284 optic fissure optic fissure closure incomplete , abnormal
Show

 ZFA:0001557 pronephric glomerulus pronephric glomerulus absent , abnormal
Show

 ZFA:0001617 otolith otolith increased amount , abnormal
Show

 ZFA:0007057 ocular blood vessel ocular blood vessel malformed , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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