ENSDARG00000037962


Danio rerio

Features
Gene ID: ENSDARG00000037962
  
Biological name :psmb7
  
Synonyms : proteasome subunit beta 7 / psmb7
  
Possible biological names infered from orthology : P70195 / Proteasome subunit beta type-7 / Q99436
  
Species: Danio rerio
  
Chr. number: 21
Strand: 1
Band:
Gene start: 8341774
Gene end: 8352095
  
Corresponding Affymetrix probe sets: Dr.19896.1.S1_at (Zebrafish Array)   NM_001045564_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000112303
Ensembl peptide - ENSDARP00000055324
Ensembl peptide - ENSDARP00000118428
NCBI entrez gene - 64278     See in Manteia.
RefSeq - NM_001045564
RefSeq - XM_021468901
RefSeq Peptide - NP_001039029
swissprot - F1Q5N4
swissprot - E9QJ03
swissprot - Q7T002
ZFIN ID - ZDB-GENE-001208-4
Ensembl - ENSDARG00000037962
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PSMB7ENSGALG00000001103Gallus gallus
 PSMB7ENSG00000136930Homo sapiens
 Psmb7ENSMUSG00000026750Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
psmb10 / proteasome subunit beta 10 / P40306* / O35955* / AC040162.1* / Proteasome subunit beta type-10 *ENSDARG0000004378168
psmb13a / proteasome subunit beta 13aENSDARG0000000165658


Protein motifs (from Interpro)
Interpro ID Name
 IPR000243  Peptidase T1A, proteasome beta-subunit
 IPR001353  Proteasome, subunit alpha/beta
 IPR016050  Proteasome beta-type subunit, conserved site
 IPR023333  Proteasome B-type subunit
 IPR024689  Proteasome beta subunit, C-terminal
 IPR029055  Nucleophile aminohydrolases, N-terminal
 IPR035216  Proteasome subunit beta 7


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0051603 proteolysis involved in cellular protein catabolic process IEA
 cellular_componentGO:0000502 proteasome complex IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005839 proteasome core complex IEA
 molecular_functionGO:0004175 endopeptidase activity IEA
 molecular_functionGO:0004298 threonine-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Activation of NF-kappaB in B cells
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
Cross-presentation of soluble exogenous antigens (endosomes)
Autodegradation of Cdh1 by Cdh1:APC/C
APC/C:Cdc20 mediated degradation of Securin
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
SCF(Skp2)-mediated degradation of p27/p21
Degradation of beta-catenin by the destruction complex
Downstream TCR signaling
Separation of Sister Chromatids
FCERI mediated NF-kB activation
Autodegradation of the E3 ubiquitin ligase COP1
Regulation of ornithine decarboxylase (ODC)
ABC-family proteins mediated transport
AUF1 (hnRNP D0) binds and destabilizes mRNA
Asymmetric localization of PCP proteins
Degradation of AXIN
Degradation of DVL
Dectin-1 mediated noncanonical NF-kB signaling
CLEC7A (Dectin-1) signaling
Degradation of GLI1 by the proteasome
Hedgehog on state
Regulation of RAS by GAPs
TNFR2 non-canonical NF-kB pathway
NIK-->noncanonical NF-kB signaling
MAPK6/MAPK4 signaling
UCH proteinases
Ub-specific processing proteases
Neutrophil degranulation
CDT1 association with the CDC6:ORC:origin complex
Orc1 removal from chromatin
CDK-mediated phosphorylation and removal of Cdc6
Ubiquitin-dependent degradation of Cyclin D1
G2/M Checkpoints
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
The role of GTSE1 in G2/M progression after G2 checkpoint
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Regulation of RUNX2 expression and activity
Regulation of RUNX3 expression and activity
Regulation of PTEN stability and activity
Neddylation
Interleukin-1 signaling
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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