ENSDARG00000039827


Danio rerio

Features
Gene ID: ENSDARG00000039827
  
Biological name :bbs5
  
Synonyms : Bardet-Biedl syndrome 5 / bbs5 / Q7ZWB7
  
Possible biological names infered from orthology : AC093899.2 / Bardet-Biedl syndrome 5 protein homolog / Q8N3I7 / Q9CZQ9
  
Species: Danio rerio
  
Chr. number: 9
Strand: -1
Band:
Gene start: 48284606
Gene end: 48296469
  
Corresponding Affymetrix probe sets: Dr.20665.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000058254
NCBI entrez gene - 393269     See in Manteia.
swissprot - Q7ZWB7
ZFIN ID - ZDB-GENE-040426-1083
Ensembl - ENSDARG00000039827
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BBS5ENSGALG00000009846Gallus gallus
 AC093899.2ENSG00000251569Homo sapiens
 BBS5ENSG00000163093Homo sapiens
 Bbs5ENSMUSG00000063145Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006606  Bardet-Biedl syndrome 5 protein
 IPR011993  PH-like domain superfamily
 IPR014003  DM16 repeat
 IPR030804  Bardet-Biedl syndrome 5 protein/sex-determination protein fem-3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001947 heart looping IMP
 biological_processGO:0007369 gastrulation IMP
 biological_processGO:0032402 melanosome transport TAS
 biological_processGO:0042051 compound eye photoreceptor development IMP
 biological_processGO:0046907 intracellular transport IMP
 biological_processGO:0048749 compound eye development IMP
 biological_processGO:0051877 pigment granule aggregation in cell center IMP
 biological_processGO:0060271 cilium assembly IBA
 biological_processGO:0070121 Kupffer"s vesicle development IMP
 biological_processGO:0072116 pronephros formation IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0034464 BBSome IBA
 cellular_componentGO:0036064 ciliary basal body IBA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0060170 ciliary membrane IEA
 molecular_functionGO:0032266 phosphatidylinositol-3-phosphate binding IBA


Pathways (from Reactome)
Pathway description
BBSome-mediated cargo-targeting to cilium


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000035 lens lens detached from retina , abnormal
Show

 ZFA:0000046 retinal neural layer retinal neural layer malformed , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000114 heart heart edematous , abnormal
Show

 ZFA:0000135 notochord notochord kinked , abnormal
Show

 ZFA:0000150 pronephric duct pronephric duct dilated , abnormal
pronephric duct ciliated cell irregular density , abnormal
pronephric duct cystic , abnormal
Show

 ZFA:0000155 somite somite increased width , abnormal
Show

 ZFA:0001058 caudal fin caudal fin curved , abnormal
Show

 ZFA:0001094 whole organism whole organism anterior-posterior axis decreased length , abnormal
Show

 ZFA:0001464 retinal outer nuclear layer retinal outer nuclear layer absent , abnormal
Show

 ZFA:0005781 cloaca cloaca cystic , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr