ENSDARG00000041706


Danio rerio

Features
Gene ID: ENSDARG00000041706
  
Biological name :vgll2a
  
Synonyms : vestigial-like family member 2a / vgll2a
  
Possible biological names infered from orthology : Q8BGW8 / Q8N8G2 / vestigial like family member 2 / VGLL2
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 42431542
Gene end: 42439896
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000061048
NCBI entrez gene - 556856     See in Manteia.
RefSeq - NM_001025486
RefSeq Peptide - NP_001020657
swissprot - F1QQZ3
ZFIN ID - ZDB-GENE-050913-38
Ensembl - ENSDARG00000041706
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 VGLL2ENSGALG00000014917Gallus gallus
 VGLL2ENSG00000170162Homo sapiens
 Vgll2ENSMUSG00000049641Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
vgll3 / vestigial-like family member 3 / A8MV65*ENSDARG0000003830532
vgll2b / vestigial-like family member 2bENSDARG0000005377332


Protein motifs (from Interpro)
Interpro ID Name
 IPR011520  Vestigial familiy


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0014032 neural crest cell development IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IBA
 biological_processGO:0048703 embryonic viscerocranium morphogenesis IMP
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding IBA
 molecular_functionGO:0003713 transcription coactivator activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001106 pharyngeal pouch pharyngeal pouch decreased length , abnormal
pharyngeal pouch increased width , abnormal
Show

 ZFA:0001174 pharyngeal epithelium pharyngeal epithelium disorganized , abnormal
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 ZFA:0001205 Meckel s cartilage Meckels cartilage hypoplastic , abnormal
Show

 ZFA:0001306 pharyngeal arch pharyngeal arch morphology , abnormal
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 ZFA:0001399 palatoquadrate cartilage palatoquadrate cartilage hypoplastic , abnormal
Show

 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage hypoplastic , abnormal
Show

 ZFA:0001405 ethmoid cartilage ethmoid cartilage decreased size , abnormal
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 ZFA:0001422 hyosymplectic cartilage hyosymplectic cartilage hypoplastic , abnormal
Show

 ZFA:0001460 pharyngeal arch cartilage pharyngeal arch cartilage hypoplastic , abnormal
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 ZFA:0001613 pharyngeal arch 3-7 pharyngeal arch 3-7 lacks all parts of type ceratobranchial 2 cartilage , abnormal
pharyngeal arch 3-7 lacks all parts of type ceratobranchial 3 cartilage , abnormal
pharyngeal arch 3-7 lacks all parts of type ceratobranchial 4 cartilage , abnormal
pharyngeal arch 3-7 lacks all parts of type ceratobranchial 1 cartilage , abnormal
pharyngeal arch 3-7 lacks all parts of type ceratobranchial 5 cartilage , abnormal
Show

 ZFA:0009003 cranial neural crest cell cranial neural crest cell decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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