ENSDARG00000042747


Danio rerio

Features
Gene ID: ENSDARG00000042747
  
Biological name :coasy
  
Synonyms : coasy / CoA synthase
  
Possible biological names infered from orthology : Coenzyme A synthase / Ppat / Q13057 / Q9DBL7
  
Species: Danio rerio
  
Chr. number: 24
Strand: -1
Band:
Gene start: 36275660
Gene end: 36301072
  
Corresponding Affymetrix probe sets: Dr.17697.1.A1_at (Zebrafish Array)   NM_001004577_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000062735
NCBI entrez gene - 447838     See in Manteia.
RefSeq - NM_001004577
RefSeq Peptide - NP_001004577
swissprot - Q66HW0
ZFIN ID - ZDB-GENE-040912-137
Ensembl - ENSDARG00000042747
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 COASYENSGALG00000028866Gallus gallus
 COASYENSG00000068120Homo sapiens
 PpatENSMUSG00000001755Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001977  Dephospho-CoA kinase
 IPR004821  Cytidyltransferase-like domain
 IPR014729  Rossmann-like alpha/beta/alpha sandwich fold
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009058 biosynthetic process IEA
 biological_processGO:0015937 coenzyme A biosynthetic process IBA
 biological_processGO:0016310 phosphorylation IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004140 dephospho-CoA kinase activity IBA
 molecular_functionGO:0004595 pantetheine-phosphate adenylyltransferase activity IBA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Coenzyme A biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain morphology , abnormal
brain morphology , ameliorated
brain cell death increased process quality , abnormal
Show

 ZFA:0000029 hindbrain hindbrain decreased distribution , abnormal
hindbrain morphology , abnormal
Show

 ZFA:0000037 anatomical structure anatomical structure spatial pattern , ameliorated
anatomical structure decreased distribution , abnormal
Show

 ZFA:0000042 midbrain hindbrain boundary midbrain hindbrain boundary spatial pattern , ameliorated
midbrain hindbrain boundary decreased distribution , abnormal
Show

 ZFA:0000075 spinal cord spinal cord neuron decreased distribution , abnormal
Show

 ZFA:0000077 tail bud tail bud spatial pattern , ameliorated
tail bud decreased distribution , abnormal
Show

 ZFA:0000079 telencephalon telencephalon decreased distribution , abnormal
telencephalon spatial pattern , ameliorated
Show

 ZFA:0000084 yolk yolk increased size , abnormal
Show

 ZFA:0000101 diencephalon diencephalon decreased distribution , abnormal
Show

 ZFA:0000107 eye eye spatial pattern , ameliorated
eye decreased distribution , abnormal
Show

 ZFA:0000120 lateral line ganglion lateral line ganglion spatial pattern , ameliorated
lateral line ganglion decreased distribution , abnormal
Show

 ZFA:0000128 midbrain midbrain morphology , abnormal
Show

 ZFA:0000135 notochord notochord spatial pattern , ameliorated
notochord decreased distribution , abnormal
Show

 ZFA:0000155 somite somite shape , abnormal
somite spatial pattern , ameliorated
somite decreased distribution , abnormal
Show

 ZFA:0000160 tegmentum tegmentum decreased distribution , abnormal
Show

 ZFA:0000279 segmental plate segmental plate spatial pattern , abnormal
segmental plate spatial pattern , ameliorated
Show

 ZFA:0001094 whole organism whole organism wholly dorsalized , abnormal
whole organism amount , ameliorated
whole organism decreased amount , abnormal
Show

 ZFA:0001114 head head edematous , abnormal
Show

 ZFA:0001115 trunk trunk decreased thickness , abnormal
Show

 ZFA:0001117 post-vent region post-vent region morphology , abnormal
post-vent region morphology , ameliorated
post-vent region curved , abnormal
post-vent region edematous , abnormal
post-vent region kinked , abnormal
post-vent region cell death increased process quality , abnormal
Show

 ZFA:0001162 anal fin anal fin decreased size , abnormal
anal fin hypoplastic , abnormal
Show

 ZFA:0001285 intersegmental vessel intersegmental vessel hypoplastic , abnormal
intersegmental vessel physical object quality , ameliorated
Show

 ZFA:0001462 somite border somite border structure , abnormal
Show

 ZFA:0007046 midbrain hindbrain boundary neural rod midbrain hindbrain boundary neural rod decreased distribution , abnormal
Show

 ZFA:0009256 nucleate erythrocyte nucleate erythrocyte decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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