ENSDARG00000054454


Danio rerio

Features
Gene ID: ENSDARG00000054454
  
Biological name :epha4a
  
Synonyms : epha4a / eph receptor A4a
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 2
Strand: -1
Band:
Gene start: 40067808
Gene end: 40136024
  
Corresponding Affymetrix probe sets: Dr.25694.1.S1_at (Zebrafish Array)   Dr.6381.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000123962
Ensembl peptide - ENSDARP00000089403
Ensembl peptide - ENSDARP00000124775
Ensembl peptide - ENSDARP00000143572
NCBI entrez gene - 64271     See in Manteia.
RefSeq - NM_001005919
RefSeq Peptide - NP_001005919
swissprot - F1QIM7
swissprot - A0A286Y8S1
swissprot - F8W2C8
swissprot - F8W481
ZFIN ID - ZDB-GENE-001207-7
Ensembl - ENSDARG00000054454
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000040949Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LO016987.1ENSDARG0000010357631
CABZ01071972.1 / EPHA10* / Q5JZY3* / EPH receptor A10*ENSDARG0000007532116
FQ377603.1ENSDARG0000010921515


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001090  Ephrin receptor ligand binding domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR001426  Tyrosine-protein kinase, receptor class V, conserved site
 IPR001660  Sterile alpha motif domain
 IPR003961  Fibronectin type III
 IPR008266  Tyrosine-protein kinase, active site
 IPR008979  Galactose-binding-like domain superfamily
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR011009  Protein kinase-like domain superfamily
 IPR011641  Tyrosine-protein kinase ephrin type A/B receptor-like
 IPR013761  Sterile alpha motif/pointed domain superfamily
 IPR013783  Immunoglobulin-like fold
 IPR016257  Ephrin receptor type-A /type-B
 IPR017441  Protein kinase, ATP binding site
 IPR020635  Tyrosine-protein kinase, catalytic domain
 IPR027936  Ephrin receptor, transmembrane domain
 IPR034270  Ephrin type-A receptor 4, ligand binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0048013 ephrin receptor signaling pathway IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0005003 ephrin receptor activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000713 abducens motor nucleus abducens motor nucleus fused with abducens motor nucleus , abnormal
abducens motor nucleus adjacent to abducens motor nucleus , abnormal
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 ZFA:0000823 rhombomere 5 rhombomere 5 rhombomere boundary formation process quality , abnormal
Show

 ZFA:0000948 rhombomere 3 rhombomere 3 rhombomere boundary formation process quality , abnormal
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 ZFA:0001064 rhombomere rhombomere compartment boundary disorganized , abnormal
Show

 ZFA:0001365 trigeminal motor nucleus trigeminal motor nucleus adjacent to trigeminal motor nucleus , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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