ENSDARG00000055786


Danio rerio

Features
Gene ID: ENSDARG00000055786
  
Biological name :prss23
  
Synonyms : protease, serine, 23 / prss23
  
Possible biological names infered from orthology : O95084 / Q9D6X6 / serine protease 23
  
Species: Danio rerio
  
Chr. number: 14
Strand: -1
Band:
Gene start: 30802465
Gene end: 30808174
  
Corresponding Affymetrix probe sets: Dr.23352.1.S1_at (Zebrafish Array)   Dr.26293.1.A1_at (Zebrafish Array)   XM_001338357_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000072648
Ensembl peptide - ENSDARP00000142618
NCBI entrez gene - 563933     See in Manteia.
RefSeq - XM_001338357
swissprot - F1R3E8
ZFIN ID - ZDB-GENE-030131-9149
Ensembl - ENSDARG00000055786
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000005747Gallus gallus
 O95084ENSG00000150687Homo sapiens
 Prss23ENSMUSG00000039405Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
prss35 / protease, serine, 35 / Q8C0F9* / Q8N3Z0* / serine protease 35* / Inactive serine protease 35 *ENSDARG0000010069145
LO018513.1 / PRSS35* / Q8N3Z0* / serine protease 35*ENSDARG0000005908144


Protein motifs (from Interpro)
Interpro ID Name
 IPR001254  Serine proteases, trypsin domain
 IPR008256  Peptidase S1B
 IPR009003  Peptidase S1, PA clan
 IPR018114  Serine proteases, trypsin family, histidine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003160 endocardium morphogenesis IMP
 biological_processGO:0003171 atrioventricular valve development IMP
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0008593 regulation of Notch signaling pathway IMP
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000114 heart heart morphology , abnormal
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 ZFA:0001616 atrioventricular canal endocardium atrioventricular canal endocardium morphology , abnormal
atrioventricular canal endocardium cell decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr