ENSDARG00000057317


Danio rerio

Features
Gene ID: ENSDARG00000057317
  
Biological name :nexn
  
Synonyms : nexilin (F actin binding protein) / nexn
  
Possible biological names infered from orthology : Nexilin / Q0ZGT2 / Q7TPW1
  
Species: Danio rerio
  
Chr. number: 8
Strand: -1
Band:
Gene start: 18515711
Gene end: 18537882
  
Corresponding Affymetrix probe sets: Dr.4859.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000091331
Ensembl peptide - ENSDARP00000145943
Ensembl peptide - ENSDARP00000148589
Ensembl peptide - ENSDARP00000124483
Ensembl peptide - ENSDARP00000124600
Ensembl peptide - ENSDARP00000124827
NCBI entrez gene - 573301     See in Manteia.
RefSeq - NM_001083855
RefSeq Peptide - NP_001077324
swissprot - F1QGT0
swissprot - F8W277
swissprot - F8W2U9
swissprot - Q5U3J5
ZFIN ID - ZDB-GENE-041114-92
Ensembl - ENSDARG00000057317
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NEXNENSGALG00000008945Gallus gallus
 NEXNENSG00000162614Homo sapiens
 NexnENSMUSG00000039103Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030334 regulation of cell migration IBA
 biological_processGO:0048739 cardiac muscle fiber development IMP
 biological_processGO:0051493 regulation of cytoskeleton organization IBA
 cellular_componentGO:0030018 Z disc IDA
 molecular_functionGO:0051015 actin filament binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000009 cardiac ventricle cardiac ventricle increased width , abnormal
Show

 ZFA:0000114 heart heart sarcomere malformed , abnormal
heart Z disc malformed , abnormal
heart edematous , abnormal
Show

 ZFA:0000471 atrium atrium increased width , abnormal
Show

 ZFA:0009115 skeletal muscle cell skeletal muscle cell sarcomere deformed , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr