ENSDARG00000057465


Danio rerio

Features
Gene ID: ENSDARG00000057465
  
Biological name :gfpt1
  
Synonyms : gfpt1 / glutamine--fructose-6-phosphate transaminase 1
  
Possible biological names infered from orthology : Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 / P47856 / Q06210
  
Species: Danio rerio
  
Chr. number: 8
Strand: 1
Band:
Gene start: 49975160
Gene end: 50037559
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000074585
Ensembl peptide - ENSDARP00000129426
NCBI entrez gene - 567861     See in Manteia.
RefSeq - NM_001034981
RefSeq Peptide - NP_001030153
swissprot - F1QDD9
swissprot - Q3S344
swissprot - X1WGR7
ZFIN ID - ZDB-GENE-070423-1
Ensembl - ENSDARG00000057465
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GFPT1ENSGALG00000036391Gallus gallus
 GFPT1ENSG00000198380Homo sapiens
 Gfpt1ENSMUSG00000029992Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gfpt2 / glutamine-fructose-6-phosphate transaminase 2 / O94808* / Q9Z2Z9* / Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 *ENSDARG0000004409473


Protein motifs (from Interpro)
Interpro ID Name
 IPR001347  Sugar isomerase (SIS)
 IPR005855  Glucosamine-fructose-6-phosphate aminotransferase, isomerising
 IPR017932  Glutamine amidotransferase type 2 domain
 IPR029055  Nucleophile aminohydrolases, N-terminal
 IPR035466  GlmS/AgaS, SIS domain 1
 IPR035490  GlmS/FrlB, SIS domain 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002063 chondrocyte development IMP
 biological_processGO:0006002 fructose 6-phosphate metabolic process IBA
 biological_processGO:0006047 UDP-N-acetylglucosamine metabolic process IBA
 biological_processGO:0006487 protein N-linked glycosylation IBA
 biological_processGO:0007519 skeletal muscle tissue development IMP
 biological_processGO:0007528 neuromuscular junction development IMP
 biological_processGO:0030318 melanocyte differentiation IMP
 biological_processGO:0048703 embryonic viscerocranium morphogenesis IMP
 biological_processGO:1901135 carbohydrate derivative metabolic process IEA
 biological_processGO:1901137 carbohydrate derivative biosynthetic process IEA
 molecular_functionGO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity IBA
 molecular_functionGO:0097367 carbohydrate derivative binding IEA


Pathways (from Reactome)
Pathway description
Synthesis of UDP-N-acetyl-glucosamine


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000007 blood blood glucose decreased amount , abnormal
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 ZFA:0000037 anatomical structure anatomical structure amount , ameliorated
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 ZFA:0000123 liver liver fatty , abnormal
liver mitochondrion swollen , abnormal
liver lipid droplet increased amount , abnormal
liver increased amount , abnormal
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 ZFA:0000155 somite somite curved , abnormal
somite clathrin-sculpted acetylcholine transport vesicle mislocalised medially , abnormal
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 ZFA:0000242 male organism male organism glucose decreased amount , abnormal
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 ZFA:0001094 whole organism whole organism curved ventral , abnormal
whole organism decreased length , abnormal
whole organism triglyceride increased amount , abnormal
whole organism viability , abnormal
whole organism decreased life span , abnormal
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 ZFA:0001273 ventral mandibular arch ventral mandibular arch decreased size , abnormal
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 ZFA:0001422 hyosymplectic cartilage hyosymplectic cartilage disorganized , abnormal
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 ZFA:0009052 motor neuron motor neuron axon branched , abnormal
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 ZFA:0009091 melanocyte melanocyte decreased amount , abnormal
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 ZFA:0009116 slow muscle cell slow muscle cell morphology , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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