ENSDARG00000061017


Danio rerio

Features
Gene ID: ENSDARG00000061017
  
Biological name :spns2
  
Synonyms : A2SWM2 / spinster homolog 2 (Drosophila) / spns2
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 30802798
Gene end: 30924453
  
Corresponding Affymetrix probe sets: Dr.17766.1.A1_at (Zebrafish Array)   Dr.17766.2.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000080999
Ensembl peptide - ENSDARP00000129119
Ensembl peptide - ENSDARP00000100856
NCBI entrez gene - 568117     See in Manteia.
RefSeq - NM_001114455
RefSeq Peptide - NP_001107927
swissprot - A9JRX4
swissprot - A2SWM2
swissprot - G8JL22
ZFIN ID - ZDB-GENE-030131-5843
Ensembl - ENSDARG00000061017
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011701  Major facilitator superfamily
 IPR020846  Major facilitator superfamily domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001569 branching involved in blood vessel morphogenesis IDA
 biological_processGO:0001944 vasculature development IGI
 biological_processGO:0003143 embryonic heart tube morphogenesis IMP
 biological_processGO:0003319 cardioblast migration to the midline involved in heart rudiment formation IMP
 biological_processGO:0003376 sphingosine-1-phosphate signaling pathway IMP
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0048703 embryonic viscerocranium morphogenesis IGI
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0061035 regulation of cartilage development IMP
 cellular_componentGO:0005765 lysosomal membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031982 vesicle IBA
 molecular_functionGO:0046624 sphingolipid transporter activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000017 endoderm endoderm shape , abnormal
endoderm structure , abnormal
Show

 ZFA:0000114 heart heart bifurcated , abnormal
heart edematous , abnormal
heart mislocalised laterally , abnormal
heart shape , abnormal
heart duplicated , abnormal
heart split bilaterally , abnormal
heart increased amount , abnormal
Show

 ZFA:0000115 heart rudiment heart rudiment bifurcated , abnormal
Show

 ZFA:0000360 heart tube heart tube increased amount , abnormal
heart tube mislocalised laterally , abnormal
Show

 ZFA:0001058 caudal fin caudal fin blistered , abnormal
caudal fin endoderm blistered , abnormal
Show

 ZFA:0001104 pharyngeal endoderm pharyngeal endoderm disorganized , abnormal
pharyngeal endoderm mislocalised posteriorly , abnormal
Show

 ZFA:0001205 Meckel s cartilage Meckels cartilage decreased length , abnormal
Meckels cartilage hypoplastic , abnormal
Meckels cartilage malformed , abnormal
Meckels cartilage disorganized , abnormal
Meckels cartilage aplastic , abnormal
Show

 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton morphology , abnormal
mandibular arch skeleton shape , abnormal
mandibular arch skeleton size , abnormal
mandibular arch skeleton mislocalised , abnormal
mandibular arch skeleton hypoplastic , abnormal
mandibular arch skeleton osteoblast disorganized , abnormal
mandibular arch skeleton osteoblast increased area , abnormal
Show

 ZFA:0001273 ventral mandibular arch ventral mandibular arch disorganized , abnormal
Show

 ZFA:0001285 intersegmental vessel intersegmental vessel shortened , abnormal
Show

 ZFA:0001321 neurocranial trabecula neurocranial trabecula hypoplastic , abnormal
Show

 ZFA:0001379 pharyngeal ectoderm pharyngeal ectoderm disorganized , abnormal
pharyngeal ectoderm increased area , abnormal
Show

 ZFA:0001399 palatoquadrate cartilage palatoquadrate cartilage decreased length , abnormal
palatoquadrate cartilage aplastic , abnormal
Show

 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage decreased length , abnormal
Show

 ZFA:0001405 ethmoid cartilage ethmoid cartilage hypoplastic , abnormal
Show

 ZFA:0001612 pharyngeal arch 1 pharyngeal arch 1 morphology , abnormal
pharyngeal arch 1 embryonic morphogenesis disrupted , abnormal
Show

 ZFA:0005463 oral ectoderm oral ectoderm hypoplastic , abnormal
oral ectoderm disorganized , abnormal
oral ectoderm mislocalised anteriorly , abnormal
Show

 ZFA:0005597 median fin median fin blistered , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   


© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr