ENSDARG00000061259


Danio rerio

Features
Gene ID: ENSDARG00000061259
  
Biological name :sost
  
Synonyms : sclerostin / sost
  
Possible biological names infered from orthology : Q9BQB4
  
Species: Danio rerio
  
Chr. number: 12
Strand: 1
Band:
Gene start: 27331324
Gene end: 27335652
  
Corresponding Affymetrix probe sets: Dr.23153.1.S1_at (Zebrafish Array)   XM_001340647_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000081642
NCBI entrez gene - 100000500     See in Manteia.
RefSeq - XM_001340647
RefSeq - XM_021480342
swissprot - E7EXX7
ZFIN ID - ZDB-GENE-110411-139
Ensembl - ENSDARG00000061259
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SOSTENSGALG00000009929Gallus gallus
 SOSTENSG00000167941Homo sapiens
 SostENSMUSG00000001494Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
sostdc1a / sclerostin domain containing 1a / Q9CQN4* / Q6X4U4* / SOSTDC1* / sclerostin domain containing 1* / Sclerostin domain-containing protein 1 *ENSDARG0000006889239
sostdc1b / sclerostin domain containing 1bENSDARG0000005602138


Protein motifs (from Interpro)
Interpro ID Name
 IPR006207  Cystine knot, C-terminal
 IPR008835  Sclerostin/Sclerostin domain-containing protein 1
 IPR015665  Sclerostin
 IPR029034  Cystine-knot cytokine


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030279 negative regulation of ossification IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA


Pathways (from Reactome)
Pathway description
Negative regulation of TCF-dependent signaling by WNT ligand antagonists


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr