ENSDARG00000063563


Danio rerio

Features
Gene ID: ENSDARG00000063563
  
Biological name :creb3l2
  
Synonyms : A1L224 / cAMP responsive element binding protein 3-like 2 / creb3l2
  
Possible biological names infered from orthology : Cyclic AMP-responsive element-binding protein 3-like protein 2 Processed cyclic AMP-responsive element-binding protein 3-like protein 2 / Q70SY1 / Q8BH52
  
Species: Danio rerio
  
Chr. number: 4
Strand: -1
Band:
Gene start: 4712410
Gene end: 4751983
  
Corresponding Affymetrix probe sets: Dr.17125.1.A1_at (Zebrafish Array)   NM_001080651_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000087416
Ensembl peptide - ENSDARP00000130319
Ensembl peptide - ENSDARP00000116961
NCBI entrez gene - 791169     See in Manteia.
RefSeq - NM_001080651
RefSeq Peptide - NP_001074120
swissprot - B8A5I6
swissprot - A1L224
swissprot - A0A0R4IB37
ZFIN ID - ZDB-GENE-070112-1542
Ensembl - ENSDARG00000063563
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CREB3L2ENSGALG00000012877Gallus gallus
 Q70SY1ENSG00000182158Homo sapiens
 Q8BH52ENSMUSG00000038648Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
creb3l1 / cAMP responsive element binding protein 3-like 1 / Q96BA8*ENSDARG0000001579341
creb3l3a / cAMP responsive element binding protein 3-like 3a / Q68CJ9* / Q91XE9* / CREB3L3* / cAMP responsive element binding protein 3 like 3* / Cyclic AMP-responsive element-binding prote...ENSDARG0000005622620
creb3l3b / cAMP responsive element binding protein 3-like 3b / Q68CJ9* / Q91XE9* / CREB3L3* / cAMP responsive element binding protein 3 like 3* / Cyclic AMP-responsive element-binding prote...ENSDARG0000009090319
creb3l3l / cAMP responsive element binding protein 3-like 3 like / CREB3* / O43889* / cAMP responsive element binding protein 3*ENSDARG0000002092618


Protein motifs (from Interpro)
Interpro ID Name
 IPR004827  Basic-leucine zipper domain
 IPR029804  cAMP-responsive element-binding protein 3-like protein 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002062 chondrocyte differentiation ISS
 biological_processGO:0003330 regulation of extracellular matrix constituent secretion IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006986 response to unfolded protein IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0030968 endoplasmic reticulum unfolded protein response IEA
 biological_processGO:0034976 response to endoplasmic reticulum stress ISS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0051216 cartilage development ISS
 biological_processGO:0060628 regulation of ER to Golgi vesicle-mediated transport IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005783 endoplasmic reticulum ISS
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0035497 cAMP response element binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000095 pharyngeal arch 3-7 skeleton pharyngeal arch 3-7 skeleton quality , abnormal
Show

 ZFA:0000135 notochord notochord collagen trimer mislocalised , abnormal
notochord extracellular matrix decreased thickness , abnormal
Show

 ZFA:0000431 semicircular canal semicircular canal aplastic , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased length , abnormal
Show

 ZFA:0001114 head head decreased length , abnormal
Show

 ZFA:0001115 trunk trunk decreased length , abnormal
Show

 ZFA:0001161 pectoral fin pectoral fin decreased length , abnormal
Show

 ZFA:0001205 Meckel s cartilage Meckels cartilage decreased length , abnormal
Meckels cartilage malformed , abnormal
Meckels cartilage chondrocyte malformed , abnormal
Show

 ZFA:0001399 palatoquadrate cartilage palatoquadrate cartilage decreased length , abnormal
palatoquadrate cartilage malformed , abnormal
Show

 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage decreased length , abnormal
ceratohyal cartilage malformed , abnormal
Show

 ZFA:0001458 cranial cartilage cranial cartilage fibrillar collagen trimer decreased mass , abnormal
cranial cartilage extracellular matrix decreased mass , abnormal
Show

 ZFA:0001460 pharyngeal arch cartilage pharyngeal arch cartilage decreased size , abnormal
Show

 ZFA:0009027 chondroblast chondroblast spatial pattern , abnormal
Show

 ZFA:0009084 chondrocyte chondrocyte endoplasmic reticulum distended , abnormal
Show

 ZFA:0009091 melanocyte melanocyte melanosome circular , abnormal
melanocyte melanosome immature , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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