ENSDARG00000074271


Danio rerio

Features
Gene ID: ENSDARG00000074271
  
Biological name :wrb
  
Synonyms : Q6DRM0 / tryptophan rich basic protein / wrb
  
Possible biological names infered from orthology : O00258 / Q8K0D7
  
Species: Danio rerio
  
Chr. number: 15
Strand: 1
Band:
Gene start: 5901970
Gene end: 5916820
  
Corresponding Affymetrix probe sets: Dr.16768.1.A1_at (Zebrafish Array)   Dr.16768.2.S1_at (Zebrafish Array)   NM_001003413_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000100769
NCBI entrez gene - 335756     See in Manteia.
RefSeq - NM_001003413
RefSeq Peptide - NP_001003413
swissprot - Q6DRM0
ZFIN ID - ZDB-GENE-030131-7696
Ensembl - ENSDARG00000074271
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 WRBENSGALG00000016070Gallus gallus
 WRBENSG00000182093Homo sapiens
 WrbENSMUSG00000023147Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR028945  WRB/Get1 family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007507 heart development IMP
 biological_processGO:0010996 response to auditory stimulus IMP
 biological_processGO:0060041 retina development in camera-type eye IMP
 biological_processGO:0071816 tail-anchored membrane protein insertion into ER membrane IMP
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000076 swim bladder swim bladder uninflated , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000143 retinal photoreceptor layer retinal photoreceptor layer quality , abnormal
retinal photoreceptor layer has fewer parts of type eye photoreceptor cell , abnormal
Show

 ZFA:0000166 lateral crista lateral crista hair cell has fewer parts of type hair cell ribbon synapse, abnormal
Show

 ZFA:0000217 inner ear inner ear quality , abnormal
inner ear hair cell decreased distribution , abnormal
inner ear hair cell decreased amount , abnormal
Show

 ZFA:0000243 neuromast neuromast decreased distribution , abnormal
neuromast decreased amount , abnormal
Show

 ZFA:0001094 whole organism whole organism absent , abnormal
whole organism lacks all parts of type swim bladder , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
Show

 ZFA:0001329 retinal inner plexiform layer retinal inner plexiform layer decreased amount , abnormal
Show

 ZFA:0001330 retinal outer plexiform layer retinal outer plexiform layer disorganized , abnormal
retinal outer plexiform layer decreased amount , abnormal
retinal outer plexiform layer synapse assembly decreased occurrence , abnormal
retinal outer plexiform layer modulation of chemical synaptic transmission decreased process quality , abnormal
retinal outer plexiform layer synapse morphology , abnormal
Show

 ZFA:0001466 photoreceptor outer segment layer photoreceptor outer segment layer disorganized , abnormal
Show

 ZFA:0007000 macula saccule macula saccule hair cell has fewer parts of type hair cell synaptic vesicle, abnormal
Show

 ZFA:0009262 retinal cone cell retinal cone cell synaptic transmission, glutamatergic decreased process quality , abnormal
retinal cone cell cytoskeleton of presynaptic active zone decreased size , abnormal
retinal cone cell cytoskeleton of presynaptic active zone decreased amount , abnormal
Show

 ZFA:0009319 ON-bipolar cell ON-bipolar cell synaptic transmission, glutamatergic decreased process quality , abnormal
Show

 ZFA:0009366 hair cell hair cell basolateral plasma membrane decreased amount , abnormal
hair cell cytoskeleton of presynaptic active zone has fewer parts of type hair cell synaptic vesicle, abnormal
hair cell ribbon synapse has fewer parts of type hair cell synaptic vesicle, abnormal
hair cell presynaptic active zone organization decreased process quality , abnormal
Show

 ZFA:0009367 neuromast hair cell neuromast hair cell kinocilium decreased length , abnormal
neuromast hair cell basolateral plasma membrane decreased amount , abnormal
neuromast hair cell decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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