ENSDARG00000088805


Danio rerio

Features
Gene ID: ENSDARG00000088805
  
Biological name :nes
  
Synonyms : nes / nestin / P86839
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 16
Strand: 1
Band:
Gene start: 29043813
Gene end: 29057849
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000112046
NCBI entrez gene - 100150939     See in Manteia.
swissprot - P86839
ZFIN ID - ZDB-GENE-071119-2
Ensembl - ENSDARG00000088805
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
synm / synemin, intermediate filament protein / O15061* / Q70IV5* / synemin*ENSDARG0000006235012


Protein motifs (from Interpro)
Interpro ID Name
 IPR001664  Intermediate filament protein
 IPR018039  Intermediate filament protein, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0007420 brain development IMP
 biological_processGO:0021545 cranial nerve development IMP
 biological_processGO:0030844 positive regulation of intermediate filament depolymerization ISS
 biological_processGO:0031076 embryonic camera-type eye development IMP
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:2000179 positive regulation of neural precursor cell proliferation ISS
 cellular_componentGO:0005882 intermediate filament IEA
 molecular_functionGO:0005198 structural molecule activity IEA
 molecular_functionGO:0019215 intermediate filament binding ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain apoptotic , abnormal
brain decreased size , abnormal
brain hydrocephalic , abnormal
Show

 ZFA:0000029 hindbrain hindbrain apoptotic , abnormal
hindbrain decreased size , abnormal
hindbrain disorganized , abnormal
Show

 ZFA:0000035 lens lens hypoplastic , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
eye disorganized , abnormal
eye apoptotic , abnormal
Show

 ZFA:0000110 fourth ventricle fourth ventricle dilated , abnormal
Show

 ZFA:0000128 midbrain midbrain decreased size , abnormal
midbrain apoptotic , abnormal
midbrain disorganized , abnormal
Show

 ZFA:0000152 retina retina disorganized , abnormal
Show

 ZFA:0000159 tectal ventricle tectal ventricle dilated , abnormal
Show

 ZFA:0000396 nervous system nervous system axon spatial pattern , abnormal
Show

 ZFA:0000405 cranial nerve III cranial nerve III decreased size , abnormal
Show

 ZFA:0000445 optic tectum optic tectum decreased size , abnormal
Show

 ZFA:0000453 cranial nerve X cranial nerve X morphology , abnormal
cranial nerve X position , abnormal
Show

 ZFA:0000600 cranial nerve IV cranial nerve IV decreased size , abnormal
Show

 ZFA:0000664 cranial nerve VII cranial nerve VII decreased size , abnormal
cranial nerve VII disorganized , abnormal
Show

 ZFA:0000697 cranial nerve V cranial nerve V decreased size , abnormal
cranial nerve V disorganized , abnormal
Show

 ZFA:0001114 head head malformed , abnormal
head decreased size , abnormal
Show

 ZFA:0009073 glial cell glial cell decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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