ENSDARG00000098080


Danio rerio

Features
Gene ID: ENSDARG00000098080
  
Biological name :gnl2
  
Synonyms : gnl2 / guanine nucleotide binding protein-like 2 (nucleolar)
  
Possible biological names infered from orthology : G protein nucleolar 2 / Nucleolar GTP-binding protein 2 / Q13823 / Q99LH1
  
Species: Danio rerio
  
Chr. number: 16
Strand: 1
Band:
Gene start: 33902006
Gene end: 33925877
  
Corresponding Affymetrix probe sets: Dr.16124.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000140260
Ensembl peptide - ENSDARP00000140768
NCBI entrez gene - 793727     See in Manteia.
RefSeq - NM_213224
RefSeq Peptide - NP_998389
swissprot - A0A0R4IXF1
swissprot - A0A0R4IUN4
ZFIN ID - ZDB-GENE-040426-2317
Ensembl - ENSDARG00000098080
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GNL2ENSGALG00000001973Gallus gallus
 GNL2ENSG00000134697Homo sapiens
 Gnl2ENSMUSG00000028869Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006073  GTP binding domain
 IPR012971  Nucleolar GTP-binding protein 2, N-terminal domain
 IPR023179  GTP-binding protein, orthogonal bundle domain superfamily
 IPR024929  Nucleolar GTP-binding protein 2
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR030378  Circularly permuted (CP)-type guanine nucleotide-binding (G) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IMP
 biological_processGO:0003407 neural retina development IMP
 biological_processGO:0007096 regulation of exit from mitosis IMP
 biological_processGO:0045664 regulation of neuron differentiation IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000024 retinal ganglion cell layer retinal ganglion cell layer immature , abnormal
Show

 ZFA:0000029 hindbrain hindbrain physical object quality , abnormal
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 ZFA:0000042 midbrain hindbrain boundary midbrain hindbrain boundary decreased thickness , abnormal
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 ZFA:0000046 retinal neural layer retinal neural layer poorly differentiated , abnormal
retinal neural layer central region proliferative , abnormal
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 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000079 telencephalon telencephalon decreased size , abnormal
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 ZFA:0000101 diencephalon diencephalon physical object quality , abnormal
diencephalon dorsal region physical object quality , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000110 fourth ventricle fourth ventricle hydrocephalic , abnormal
fourth ventricle increased volume , abnormal
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 ZFA:0000119 retinal inner nuclear layer retinal inner nuclear layer immature , abnormal
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 ZFA:0000128 midbrain midbrain physical object quality , abnormal
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 ZFA:0000368 integument integument discolored , abnormal
integument rough , abnormal
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 ZFA:0000445 optic tectum optic tectum apoptotic , abnormal
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 ZFA:0001094 whole organism whole organism decreased size , abnormal
whole organism dead , abnormal
whole organism cytosolic ribosome decreased amount , abnormal
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 ZFA:0001114 head head decreased size , abnormal
head apoptotic , abnormal
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 ZFA:0001117 post-vent region post-vent region apoptotic , abnormal
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 ZFA:0001259 forebrain ventricle forebrain ventricle increased volume , abnormal
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 ZFA:0001278 posterior chamber swim bladder posterior chamber swim bladder uninflated , abnormal
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 ZFA:0001464 retinal outer nuclear layer retinal outer nuclear layer immature , abnormal
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 ZFA:0009255 amacrine cell amacrine cell decreased amount , abnormal
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 ZFA:0009262 retinal cone cell retinal cone cell absent , abnormal
retinal cone cell decreased amount , abnormal
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 ZFA:0009280 Muller cell Muller cell absent , abnormal
Muller cell mislocalised , abnormal
Muller cell decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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