ENSDARG00000100633


Danio rerio

Features
Gene ID: ENSDARG00000100633
  
Biological name :zgc:114200
  
Synonyms : zgc:114200
  
Possible biological names infered from orthology : APH1A / aph-1 homolog A, gamma-secretase subunit / Gamma-secretase subunit APH-1A / Q8BVF7 / Q96BI3
  
Species: Danio rerio
  
Chr. number: 10
Strand: 1
Band:
Gene start: 6383270
Gene end: 6409781
  
Corresponding Affymetrix probe sets: Dr.17724.1.A1_at (Zebrafish Array)   Dr.17724.1.A1_x_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000133858
swissprot - A0A0R4IF34
ZFIN ID - ZDB-GENE-050913-96
Ensembl - ENSDARG00000100633
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000002578Gallus gallus
 APH1AENSG00000117362Homo sapiens
 Aph1aENSMUSG00000015750Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
aph1b / Q8JHE9 / APH1B gamma secretase subunit / Aph1c* / Q9DCZ9* / Q8C7N7* / Q8WW43* / Gamma-secretase subunit APH-1B * / Putative gamma-secretase subunit APH-1C * / aph-1 homolog B, gamma...ENSDARG0000000561263


Protein motifs (from Interpro)
Interpro ID Name
 IPR009294  Gamma-secretase subunit Aph-1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016485 protein processing IEA
 biological_processGO:0043085 positive regulation of catalytic activity IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
Nuclear signaling by ERBB4
Regulated proteolysis of p75NTR
EPH-ephrin mediated repulsion of cells
NOTCH3 Activation and Transmission of Signal to the Nucleus
Noncanonical activation of NOTCH3


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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