ENSDARG00000101631


Danio rerio

Features
Gene ID: ENSDARG00000101631
  
Biological name :etfa
  
Synonyms : electron-transfer-flavoprotein, alpha polypeptide / etfa
  
Possible biological names infered from orthology : electron transfer flavoprotein alpha subunit / Electron transfer flavoprotein subunit alpha, mitochondrial / P13804 / Q99LC5
  
Species: Danio rerio
  
Chr. number: 25
Strand: 1
Band:
Gene start: 32755485
Gene end: 32787247
  
Corresponding Affymetrix probe sets: Dr.5170.1.S1_at (Zebrafish Array)   NM_198909_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000140482
NCBI entrez gene - 325724     See in Manteia.
RefSeq - NM_198909
RefSeq Peptide - NP_944591
swissprot - A0A0G2L6T1
swissprot - Q7ZUS9
ZFIN ID - ZDB-GENE-030131-4449
Ensembl - ENSDARG00000101631
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ETFAENSGALG00000002925Gallus gallus
 ETFAENSG00000140374Homo sapiens
 EtfaENSMUSG00000032314Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001308  Electron transfer flavoprotein alpha subunit/FixB
 IPR014729  Rossmann-like alpha/beta/alpha sandwich fold
 IPR014730  Electron transfer flavoprotein, alpha/beta-subunit, N-terminal
 IPR014731  Electron transfer flavoprotein, alpha subunit, C-terminal
 IPR018206  Electron transfer flavoprotein subunit alpha, conserved site
 IPR029035  DHS-like NAD/FAD-binding domain superfamily
 IPR033947  Electron transfer flavoprotein, alpha subunit, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009887 animal organ morphogenesis IMP
 biological_processGO:0022900 electron transport chain IEA
 biological_processGO:0031998 regulation of fatty acid beta-oxidation IMP
 biological_processGO:0070584 mitochondrion morphogenesis IMP
 molecular_functionGO:0009055 electron transfer activity IEA
 molecular_functionGO:0050660 flavin adenine dinucleotide binding IEA


Pathways (from Reactome)
Pathway description
Respiratory electron transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain mitochondrion swollen , abnormal
brain lipid droplet increased amount , abnormal
brain neuroblast (sensu Vertebrata) increased amount , abnormal
brain neuroblast (sensu Vertebrata) hyperplastic , abnormal
Show

 ZFA:0000075 spinal cord spinal cord mitochondrion swollen , abnormal
Show

 ZFA:0000114 heart heart blood plasma fatty , abnormal
heart edematous , abnormal
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 ZFA:0000123 liver liver color , abnormal
liver increased size , abnormal
liver fatty , abnormal
liver mitochondrial crista decreased mass density , abnormal
liver mitochondrion swollen , abnormal
liver lipid droplet increased amount , abnormal
Show

 ZFA:0000243 neuromast neuromast kinocilium absent , abnormal
neuromast kinocilium decreased length , abnormal
Show

 ZFA:0000529 kidney kidney morphology , abnormal
kidney mitochondrion swollen , abnormal
Show

 ZFA:0001083 ventricular zone ventricular zone glial cell (sensu Vertebrata) increased size , abnormal
Show

 ZFA:0001094 whole organism whole organism dead , abnormal
whole organism mitochondrion decreased functionality , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
Show

 ZFA:0001338 intestine intestine lipid droplet increased amount , abnormal
Show

 ZFA:0001681 grey matter grey matter morphology , abnormal
Show

 ZFA:0009053 sensory neuron sensory neuron axon disorganized , abnormal
Show

 ZFA:0009111 hepatocyte hepatocyte increased size , abnormal
hepatocyte ballooning , abnormal
Show

 ZFA:0009149 Mauthner neuron Mauthner neuron mitochondrion swollen , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000038834 etfdh / electron-transferring-flavoprotein dehydrogenase / Q16134* / Q921G7* / electron transfer flavoprotein dehydrogenase* / Electron transfer flavoprotein-ubiquinone oxidoreductase, mito...  / reaction






 

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