ENSDARG00000113205


Danio rerio

Features
Gene ID: ENSDARG00000113205
  
Biological name :HIST1H4J
  
Synonyms : HIST1H4J / histone cluster 1 H4 family member j
  
Possible biological names infered from orthology : HIST1H4H / histone cluster 1 H4 family member h / P62805
  
Species: Danio rerio
  
Chr. number: 25
Strand: 1
Band:
Gene start: 35056619
Gene end: 35056932
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000129378
swissprot - X1WGM1
Ensembl - ENSDARG00000113205
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 P62805ENSG00000197238Homo sapiens
 P62805ENSG00000158406Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
zgc:165555ENSDARG0000010535399
zgc:165555ENSDARG0000011150199
zgc:165555ENSDARG0000010538299
zgc:165555ENSDARG0000010537699
zgc:165555ENSDARG0000011003599
zgc:165555ENSDARG0000011175399
zgc:165555ENSDARG0000011295499
zgc:165555ENSDARG0000011678199
zgc:165555 / P62805* / HIST1H4C* / histone cluster 1 H4 family member c*ENSDARG0000011528199
HIST1H4E / zgc:165555 / P62805* / HIST4H4* / histone cluster 4 H4* / histone cluster 1 H4 family member e*ENSDARG0000011252899
zgc:165555 / P62805* / HIST2H4B* / histone cluster 2 H4 family member b*ENSDARG0000006154799
zgc:165555ENSDARG0000011161999
zgc:165555ENSDARG0000011015299
HIST1H4I / zgc:165555 / P62805* / histone cluster 1 H4 family member i*ENSDARG0000011081299
zgc:165555ENSDARG0000011249199
zgc:165555 / P62805* / P62806* / HIST2H4A* / Hist1h4a* / Histone H4 * / histone cluster 2 H4 family member a*ENSDARG0000010535599
zgc:165555ENSDARG0000011124799
zgc:165555ENSDARG0000011505499
zgc:165555ENSDARG0000010531899
zgc:165555ENSDARG0000011453499


Protein motifs (from Interpro)
Interpro ID Name
 IPR001951  Histone H4
 IPR004823  TATA box binding protein associated factor (TAF)
 IPR009072  Histone-fold
 IPR019809  Histone H4, conserved site
 IPR035425  CENP-T/Histone H4, histone fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006334 nucleosome assembly IBA
 biological_processGO:0006352 DNA-templated transcription, initiation IEA
 cellular_componentGO:0000786 nucleosome IEA
 cellular_componentGO:0000788 nuclear nucleosome IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005694 chromosome IEA
 molecular_functionGO:0003677 DNA binding IBA
 molecular_functionGO:0042393 histone binding IBA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
PRC2 methylates histones and DNA
Condensation of Prophase Chromosomes
Oxidative Stress Induced Senescence
Senescence-Associated Secretory Phenotype (SASP)
PKMTs methylate histone lysines
HDMs demethylate histones
HATs acetylate histones
RMTs methylate histone arginines
SIRT1 negatively regulates rRNA expression
NoRC negatively regulates rRNA expression
SUMOylation of chromatin organization proteins
B-WICH complex positively regulates rRNA expression
Transcriptional regulation by small RNAs
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Nonhomologous End-Joining (NHEJ)
Processing of DNA double-strand break ends
G2/M DNA damage checkpoint
RNA Polymerase I Promoter Opening
RNA Polymerase I Chain Elongation
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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