ENSG00000002549


Homo sapiens

Features
Gene ID: ENSG00000002549
  
Biological name :LAP3
  
Synonyms : LAP3 / leucine aminopeptidase 3 / P28838
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: p15.32
Gene start: 17577192
Gene end: 17607972
  
Corresponding Affymetrix probe sets: 217933_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000481000
Ensembl peptide - ENSP00000226299
Ensembl peptide - ENSP00000423350
Ensembl peptide - ENSP00000424724
Ensembl peptide - ENSP00000476028
NCBI entrez gene - 51056     See in Manteia.
OMIM - 170250
RefSeq - NM_015907
RefSeq Peptide - NP_056991
swissprot - H0Y983
swissprot - H0Y9Q1
swissprot - P28838
Ensembl - ENSG00000002549
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lap3ENSDARG00000061981Danio rerio
 LAP3ENSGALG00000006334Gallus gallus
 Lap3ENSMUSG00000039682Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NPEPL1 / Q8NDH3 / aminopeptidase like 1ENSG0000021544024


Protein motifs (from Interpro)
Interpro ID Name
 IPR000819  Peptidase M17, leucyl aminopeptidase, C-terminal
 IPR008283  Peptidase M17, leucyl aminopeptidase, N-terminal
 IPR011356  Peptidase M17, leucine aminopeptidase/peptidase B
 IPR023042  Peptidase M17, leucine aminopeptidase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis NAS
 biological_processGO:0019538 protein metabolic process IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus HDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005802 trans-Golgi network IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0030496 midbody IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004177 aminopeptidase activity NAS
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008235 metalloexopeptidase activity NAS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0030145 manganese ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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