ENSG00000013364


Homo sapiens

Features
Gene ID: ENSG00000013364
  
Biological name :MVP
  
Synonyms : major vault protein / MVP / Q14764
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: p11.2
Gene start: 29820394
Gene end: 29848039
  
Corresponding Affymetrix probe sets: 202180_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000455819
Ensembl peptide - ENSP00000456291
Ensembl peptide - ENSP00000457734
Ensembl peptide - ENSP00000458583
Ensembl peptide - ENSP00000486166
Ensembl peptide - ENSP00000349977
Ensembl peptide - ENSP00000378760
Ensembl peptide - ENSP00000454819
Ensembl peptide - ENSP00000454825
Ensembl peptide - ENSP00000455186
Ensembl peptide - ENSP00000455532
Ensembl peptide - ENSP00000455741
Ensembl peptide - ENSP00000457685
NCBI entrez gene - 9961     See in Manteia.
OMIM - 605088
RefSeq - NM_005115
RefSeq - NM_017458
RefSeq - NM_001293204
RefSeq - NM_001293205
RefSeq Peptide - NP_005106
RefSeq Peptide - NP_059447
RefSeq Peptide - NP_001280134
RefSeq Peptide - NP_001280133
swissprot - X5D2M8
swissprot - H3BNF2
swissprot - H3BNF6
swissprot - H3BP76
swissprot - H3BPZ2
swissprot - H3BQE7
swissprot - H3BQK6
swissprot - H3BRL2
swissprot - H3BUK7
swissprot - H3BUP3
swissprot - I3L155
swissprot - Q14764
Ensembl - ENSG00000013364
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mvpENSDARG00000021242Danio rerio
 MVPENSGALG00000040471Gallus gallus
 MvpENSMUSG00000030681Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002499  Major vault protein, N-terminal
 IPR021870  Major vault protein, shoulder domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0023057 negative regulation of signaling IDA
 biological_processGO:0031953 negative regulation of protein autophosphorylation IDA
 biological_processGO:0038127 ERBB signaling pathway IDA
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0051028 mRNA transport IEA
 biological_processGO:0061099 negative regulation of protein tyrosine kinase activity IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005643 nuclear pore IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005856 cytoskeleton IDA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0034774 secretory granule lumen TAS
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:1904813 ficolin-1-rich granule lumen TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0019903 protein phosphatase binding IDA
 molecular_functionGO:0042802 identical protein binding IPI


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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