ENSG00000023572


Homo sapiens

Features
Gene ID: ENSG00000023572
  
Biological name :GLRX2
  
Synonyms : GLRX2 / glutaredoxin 2 / Q9NS18
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q31.2
Gene start: 193090866
Gene end: 193106114
  
Corresponding Affymetrix probe sets: 219933_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000356409
Ensembl peptide - ENSP00000356410
Ensembl peptide - ENSP00000494652
NCBI entrez gene - 51022     See in Manteia.
OMIM - 606820
RefSeq - XM_017001397
RefSeq - NM_001243399
RefSeq - NM_001319291
RefSeq - NM_016066
RefSeq - NM_197962
RefSeq Peptide - NP_001306220
RefSeq Peptide - NP_057150
RefSeq Peptide - NP_932066
RefSeq Peptide - NP_001230328
swissprot - Q9NS18
Ensembl - ENSG00000023572
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 glrx2ENSDARG00000100944Danio rerio
 GLRX2ENSGALG00000034850Gallus gallus
 Glrx2ENSMUSG00000018196Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002109  Glutaredoxin
 IPR011899  Glutaredoxin, eukaryotic/virial
 IPR014025  Glutaredoxin subgroup
 IPR036249  Thioredoxin-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated NAS
 biological_processGO:0006749 glutathione metabolic process TAS
 biological_processGO:0006915 apoptotic process NAS
 biological_processGO:0007568 aging IEA
 biological_processGO:0009266 response to temperature stimulus NAS
 biological_processGO:0009966 regulation of signal transduction NAS
 biological_processGO:0010033 response to organic substance IDA
 biological_processGO:0022900 electron transport chain IEA
 biological_processGO:0030154 cell differentiation NAS
 biological_processGO:0042262 DNA protection NAS
 biological_processGO:0042542 response to hydrogen peroxide IDA
 biological_processGO:0045454 cell redox homeostasis TAS
 biological_processGO:0051775 response to redox state TAS
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0071451 cellular response to superoxide IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005759 mitochondrial matrix IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0003756 protein disulfide isomerase activity TAS
 molecular_functionGO:0008794 arsenate reductase (glutaredoxin) activity TAS
 molecular_functionGO:0009055 electron transfer activity NAS
 molecular_functionGO:0015035 protein disulfide oxidoreductase activity IEA
 molecular_functionGO:0015038 glutathione disulfide oxidoreductase activity TAS
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051536 iron-sulfur cluster binding IEA
 molecular_functionGO:0051537 2 iron, 2 sulfur cluster binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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