ENSG00000053108


Homo sapiens

Features
Gene ID: ENSG00000053108
  
Biological name :FSTL4
  
Synonyms : follistatin like 4 / FSTL4 / Q6MZW2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q31.1
Gene start: 133196455
Gene end: 133612564
  
Corresponding Affymetrix probe sets: 1564511_a_at (Human Genome U133 Plus 2.0 Array)   1565910_at (Human Genome U133 Plus 2.0 Array)   214859_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000484273
Ensembl peptide - ENSP00000265342
Ensembl peptide - ENSP00000427662
NCBI entrez gene - 23105     See in Manteia.
RefSeq - XM_017009251
RefSeq - NM_015082
RefSeq - XM_011543283
RefSeq - XM_011543284
RefSeq - XM_011543286
RefSeq Peptide - NP_055897
swissprot - Q6MZW2
swissprot - D6RHU5
Ensembl - ENSG00000053108
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fstl4ENSDARG00000044319Danio rerio
 FSTL4ENSGALG00000031487Gallus gallus
 Fstl4ENSMUSG00000036264Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FSTL5 / Q8N475 / follistatin like 5ENSG0000016884356
FSTL1 / Q12841 / follistatin like 1ENSG0000016343010


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR002350  Kazal domain
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR011992  EF-hand domain pair
 IPR013783  Immunoglobulin-like fold
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR018247  EF-Hand 1, calcium-binding site
 IPR036058  Kazal domain superfamily
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0031549 negative regulation of brain-derived neurotrophic factor receptor signaling pathway IEA
 biological_processGO:0048670 regulation of collateral sprouting IEA
 biological_processGO:0048671 negative regulation of collateral sprouting IEA
 biological_processGO:0061000 negative regulation of dendritic spine development IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0030141 secretory granule IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0048403 brain-derived neurotrophic factor binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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