ENSG00000058729


Homo sapiens

Features
Gene ID: ENSG00000058729
  
Biological name :RIOK2
  
Synonyms : Q9BVS4 / RIOK2 / RIO kinase 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q15
Gene start: 97160867
Gene end: 97183260
  
Corresponding Affymetrix probe sets: 218535_s_at (Human Genome U133 Plus 2.0 Array)   222663_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000283109
Ensembl peptide - ENSP00000421830
Ensembl peptide - ENSP00000422772
Ensembl peptide - ENSP00000424325
Ensembl peptide - ENSP00000420932
NCBI entrez gene - 55781     See in Manteia.
OMIM - 617754
RefSeq - XM_017009628
RefSeq - NM_001159749
RefSeq - NM_018343
RefSeq Peptide - NP_001153221
RefSeq Peptide - NP_060813
swissprot - Q9BVS4
swissprot - D6RB96
swissprot - H0Y8R4
swissprot - H0Y919
Ensembl - ENSG00000058729
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 riok2ENSDARG00000035264Danio rerio
 RIOK2ENSGALG00000015288Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000687  RIO kinase
 IPR011009  Protein kinase-like domain superfamily
 IPR015285  RIO2 kinase winged helix domain, N-terminal
 IPR018935  RIO kinase, conserved site
 IPR030484  Serine/threonine-protein kinase Rio2
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006364 rRNA processing TAS
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0030071 regulation of mitotic metaphase/anaphase transition IMP
 biological_processGO:0030490 maturation of SSU-rRNA IMP
 biological_processGO:0042254 ribosome biogenesis IEA
 biological_processGO:0042274 ribosomal small subunit biogenesis IMP
 biological_processGO:0046777 protein autophosphorylation IMP
 biological_processGO:2000208 positive regulation of ribosomal small subunit export from nucleus IMP
 biological_processGO:2000234 positive regulation of rRNA processing IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IMP
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0030688 preribosome, small subunit precursor IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Major pathway of rRNA processing in the nucleolus and cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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