ENSG00000069275


Homo sapiens

Features
Gene ID: ENSG00000069275
  
Biological name :NUCKS1
  
Synonyms : NUCKS1 / nuclear casein kinase and cyclin dependent kinase substrate 1 / Q9H1E3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q32.1
Gene start: 205712819
Gene end: 205750276
  
Corresponding Affymetrix probe sets: 217802_s_at (Human Genome U133 Plus 2.0 Array)   222027_at (Human Genome U133 Plus 2.0 Array)   222424_s_at (Human Genome U133 Plus 2.0 Array)   223661_at (Human Genome U133 Plus 2.0 Array)   224581_s_at (Human Genome U133 Plus 2.0 Array)   224582_s_at (Human Genome U133 Plus 2.0 Array)   226880_at (Human Genome U133 Plus 2.0 Array)   229353_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000356110
NCBI entrez gene - 64710     See in Manteia.
OMIM - 611912
RefSeq - NM_022731
RefSeq - XM_005245453
RefSeq Peptide - NP_073568
swissprot - Q9H1E3
Ensembl - ENSG00000069275
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nucks1aENSDARG00000078473Danio rerio
 nucks1bENSDARG00000012777Danio rerio
 NUCKS1ENSGALG00000000708Gallus gallus
 Nucks1ENSMUSG00000026434Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR026633  Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000724 double-strand break repair via homologous recombination IMP
 biological_processGO:0001678 cellular glucose homeostasis IEA
 biological_processGO:0006275 regulation of DNA replication IMP
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IC
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0019046 release from viral latency IMP
 biological_processGO:0031297 replication fork processing IDA
 biological_processGO:0035822 gene conversion NAS
 biological_processGO:0036297 interstrand cross-link repair IMP
 biological_processGO:0042593 glucose homeostasis IEA
 biological_processGO:0043923 positive regulation by host of viral transcription IGI
 biological_processGO:0044829 positive regulation by host of viral genome replication IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0046626 regulation of insulin receptor signaling pathway IEA
 biological_processGO:0046628 positive regulation of insulin receptor signaling pathway IEA
 biological_processGO:0060382 regulation of DNA strand elongation IMP
 biological_processGO:0071481 cellular response to X-ray IMP
 biological_processGO:1990968 modulation by host of RNA binding by virus IMP
 biological_processGO:1990969 modulation by host of viral RNA-binding transcription factor activity IGI
 cellular_componentGO:0000785 chromatin IEA
 cellular_componentGO:0000790 nuclear chromatin IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0003690 double-stranded DNA binding IDA
 molecular_functionGO:0003697 single-stranded DNA binding IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0008134 transcription factor binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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