ENSG00000071073


Homo sapiens

Features
Gene ID: ENSG00000071073
  
Biological name :MGAT4A
  
Synonyms : mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A / MGAT4A / Q9UM21
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: q11.2
Gene start: 98619106
Gene end: 98731126
  
Corresponding Affymetrix probe sets: 1569136_at (Human Genome U133 Plus 2.0 Array)   219797_at (Human Genome U133 Plus 2.0 Array)   226039_at (Human Genome U133 Plus 2.0 Array)   231283_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000404889
Ensembl peptide - ENSP00000475198
Ensembl peptide - ENSP00000264968
Ensembl peptide - ENSP00000377127
Ensembl peptide - ENSP00000386841
NCBI entrez gene - 11320     See in Manteia.
OMIM - 604623
RefSeq - NM_001160154
RefSeq - NM_012214
RefSeq Peptide - NP_001153626
RefSeq Peptide - NP_036346
swissprot - Q9UM21
swissprot - U3KPT4
Ensembl - ENSG00000071073
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mgat4aENSDARG00000063330Danio rerio
 MGAT4AENSGALG00000030780Gallus gallus
 Mgat4aENSMUSG00000026110Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MGAT4B / Q9UQ53 / mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme BENSG0000016101360
MGAT4C / Q9UBM8 / MGAT4 family member CENSG0000018205026
A6NG13 / MGAT4D / MGAT4 family member DENSG0000020530125


Protein motifs (from Interpro)
Interpro ID Name
 IPR006759  Glycosyl transferase family 54


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0006487 protein N-linked glycosylation IEA
 biological_processGO:0006491 N-glycan processing TAS
 biological_processGO:0043687 post-translational protein modification TAS
 biological_processGO:0044267 cellular protein metabolic process TAS
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005788 endoplasmic reticulum lumen TAS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0008375 acetylglucosaminyltransferase activity IEA
 molecular_functionGO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity TAS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0016758 transferase activity, transferring hexosyl groups IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation
N-Glycan antennae elongation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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