ENSG00000072080


Homo sapiens

Features
Gene ID: ENSG00000072080
  
Biological name :SPP2
  
Synonyms : Q13103 / secreted phosphoprotein 2 / SPP2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q37.1
Gene start: 234050679
Gene end: 234077134
  
Corresponding Affymetrix probe sets: 214478_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000417036
Ensembl peptide - ENSP00000168148
Ensembl peptide - ENSP00000362466
NCBI entrez gene - 6694     See in Manteia.
OMIM - 602637
RefSeq - XM_011511700
RefSeq - NM_006944
RefSeq - XM_005246102
RefSeq - XM_011511698
RefSeq - XM_011511699
RefSeq Peptide - NP_008875
swissprot - Q13103
swissprot - C9J6K0
Ensembl - ENSG00000072080
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 spp2ENSDARG00000095590Danio rerio
 SPP2ENSGALG00000004129Gallus gallus
 Spp2ENSMUSG00000026295Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR010892  Secreted phosphoprotein 24


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001501 skeletal system development TAS
 biological_processGO:0002576 platelet degranulation TAS
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 biological_processGO:0043687 post-translational protein modification TAS
 biological_processGO:0044267 cellular protein metabolic process TAS
 biological_processGO:0046849 bone remodeling IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005788 endoplasmic reticulum lumen TAS
 cellular_componentGO:0031012 extracellular matrix IDA
 cellular_componentGO:0031089 platelet dense granule lumen TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004866 endopeptidase inhibitor activity TAS


Pathways (from Reactome)
Pathway description
Platelet degranulation
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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