ENSG00000078898


Homo sapiens

Features
Gene ID: ENSG00000078898
  
Biological name :BPIFB2
  
Synonyms : BPIFB2 / BPI fold containing family B member 2 / Q8N4F0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: 1
Band: q11.21
Gene start: 33007600
Gene end: 33023709
  
Corresponding Affymetrix probe sets: 232698_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000170150
NCBI entrez gene - 80341     See in Manteia.
OMIM - 614108
RefSeq - NM_025227
RefSeq Peptide - NP_079503
swissprot - Q8N4F0
Ensembl - ENSG00000078898
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BPIFB2ENSGALG00000006666Gallus gallus
 Bpifb2ENSMUSG00000027481Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BPIFB3 / P59826 / BPI fold containing family B member 3ENSG0000018619026
BPIFB4 / P59827 / BPI fold containing family B member 4ENSG0000018619124
BPIFB6 / Q8NFQ5 / BPI fold containing family B member 6ENSG0000016710421


Protein motifs (from Interpro)
Interpro ID Name
 IPR001124  Lipid-binding serum glycoprotein, C-terminal
 IPR017942  Lipid-binding serum glycoprotein, N-terminal
 IPR017943  Bactericidal permeability-increasing protein, alpha/beta domain superfamily
 IPR030675  Lipid binding protein BPI/LBP
 IPR032942  BPI/LBP/Plunc family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0019730 antimicrobial humoral response TAS
 biological_processGO:0043687 post-translational protein modification TAS
 biological_processGO:0044267 cellular protein metabolic process TAS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005788 endoplasmic reticulum lumen TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0008289 lipid binding IEA


Pathways (from Reactome)
Pathway description
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Antimicrobial peptides
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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