ENSG00000087008


Homo sapiens

Features
Gene ID: ENSG00000087008
  
Biological name :ACOX3
  
Synonyms : ACOX3 / acyl-CoA oxidase 3, pristanoyl / O15254
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: p16.1
Gene start: 8366282
Gene end: 8440723
  
Corresponding Affymetrix probe sets: 204241_at (Human Genome U133 Plus 2.0 Array)   204242_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000427321
Ensembl peptide - ENSP00000348775
Ensembl peptide - ENSP00000413994
Ensembl peptide - ENSP00000421625
NCBI entrez gene - 8310     See in Manteia.
OMIM - 603402
RefSeq - XM_011513566
RefSeq - NM_001101667
RefSeq - NM_003501
RefSeq - XM_005248011
RefSeq - XM_005248013
RefSeq - XM_011513565
RefSeq Peptide - NP_001095137
RefSeq Peptide - NP_003492
swissprot - D6RJ89
swissprot - O15254
Ensembl - ENSG00000087008
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 acox3ENSDARG00000038865Danio rerio
 ACOX3ENSGALG00000015591Gallus gallus
 Acox3ENSMUSG00000029098Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ACOX1 / Q15067 / acyl-CoA oxidase 1ENSG0000016153329
ACOX2 / Q99424 / acyl-CoA oxidase 2ENSG0000016830628
ACOXL / Q9NUZ1 / acyl-CoA oxidase likeENSG0000015309325


Protein motifs (from Interpro)
Interpro ID Name
 IPR002655  Acyl-CoA oxidase, C-terminal
 IPR006091  Acyl-CoA oxidase/dehydrogenase, central domain
 IPR009075  Acyl-CoA dehydrogenase/oxidase C-terminal
 IPR009100  Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily
 IPR012258  Acyl-CoA oxidase
 IPR034171  Peroxisomal acyl-coenzyme A oxidase
 IPR036250  Acyl-CoA dehydrogenase-like, C-terminal
 IPR037069  Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0006635 fatty acid beta-oxidation IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase IBA
 biological_processGO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005777 peroxisome IDA
 cellular_componentGO:0005782 peroxisomal matrix TAS
 cellular_componentGO:0016020 membrane HDA
 molecular_functionGO:0003995 acyl-CoA dehydrogenase activity IBA
 molecular_functionGO:0003997 acyl-CoA oxidase activity IEA
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0016402 pristanoyl-CoA oxidase activity TAS
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016627 oxidoreductase activity, acting on the CH-CH group of donors IEA
 molecular_functionGO:0050660 flavin adenine dinucleotide binding IEA
 molecular_functionGO:0071949 FAD binding IEA


Pathways (from Reactome)
Pathway description
Beta-oxidation of pristanoyl-CoA
Peroxisomal protein import


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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