ENSG00000089154


Homo sapiens

Features
Gene ID: ENSG00000089154
  
Biological name :GCN1
  
Synonyms : GCN1 / GCN1, eIF2 alpha kinase activator homolog / Q92616
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q24.23
Gene start: 120127203
Gene end: 120194710
  
Corresponding Affymetrix probe sets: 212139_at (Human Genome U133 Plus 2.0 Array)   216232_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000300648
NCBI entrez gene - 10985     See in Manteia.
OMIM - 605614
RefSeq - NM_006836
RefSeq Peptide - NP_006827
swissprot - Q92616
Ensembl - ENSG00000089154
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gcn1ENSDARG00000058419Danio rerio
 GCN1ENSGALG00000007276Gallus gallus
 E9PVA8ENSMUSG00000041638Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold
 IPR021133  HEAT, type 2
 IPR033173  Translational activator Gcn1
 IPR034085  TOG domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IEA
 biological_processGO:0006417 regulation of translation IEA
 biological_processGO:0033554 cellular response to stress IEA
 biological_processGO:0033674 positive regulation of kinase activity IEA
 biological_processGO:0034198 cellular response to amino acid starvation IEA
 biological_processGO:0036003 positive regulation of transcription from RNA polymerase II promoter in response to stress IEA
 biological_processGO:0045859 regulation of protein kinase activity IEA
 biological_processGO:1990253 cellular response to leucine starvation IEA
 cellular_componentGO:0005737 cytoplasm NAS
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005840 ribosome NAS
 cellular_componentGO:0005844 polysome IEA
 cellular_componentGO:0016020 membrane HDA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0008135 translation factor activity, RNA binding NAS
 molecular_functionGO:0019887 protein kinase regulator activity IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0043022 ribosome binding IEA
 molecular_functionGO:0045296 cadherin binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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