ENSG00000092345


Homo sapiens

Features
Gene ID: ENSG00000092345
  
Biological name :DAZL
  
Synonyms : DAZL / deleted in azoospermia like / Q92904
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: p24.3
Gene start: 16586792
Gene end: 16670306
  
Corresponding Affymetrix probe sets: 206588_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000250863
Ensembl peptide - ENSP00000398109
Ensembl peptide - ENSP00000382373
NCBI entrez gene - 1618     See in Manteia.
OMIM - 601486
RefSeq - NM_001190811
RefSeq - NM_001351
RefSeq Peptide - NP_001177740
RefSeq Peptide - NP_001342
swissprot - Q92904
swissprot - A0A140VK77
swissprot - E7EV40
Ensembl - ENSG00000092345
  
Related genetic diseases (OMIM): 601486 - {Spermatogenic failure, susceptibility to}
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dazlENSDARG00000036214Danio rerio
 DAZLENSGALG00000011243Gallus gallus
 DazlENSMUSG00000010592Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DAZ2 / Q13117 / deleted in azoospermia 2ENSG0000020594453
DAZ1 / Q9NQZ3 / deleted in azoospermia 1ENSG0000018812052
DAZ3 / Q9NR90 / deleted in azoospermia 3ENSG0000018719151
DAZ4 / Q86SG3 / deleted in azoospermia 4ENSG0000020591649
BOLL / Q8N9W6 / boule homolog, RNA binding proteinENSG0000015243027


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR034779  Deleted in azoospermia-like
 IPR035979  RNA-binding domain superfamily
 IPR037366  BOULE/DAZ family
 IPR037551  DAZ, RNA recognition motif, vertebrates


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001556 oocyte maturation IEA
 biological_processGO:0006417 regulation of translation IEA
 biological_processGO:0007147 female meiosis II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007281 germ cell development IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0045727 positive regulation of translation IEA
 biological_processGO:0045836 positive regulation of meiotic nuclear division IEA
 biological_processGO:0045948 positive regulation of translational initiation IDA
 biological_processGO:0070935 3"-UTR-mediated mRNA stabilization IBA
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005844 polysome IEA
 cellular_componentGO:0032991 protein-containing complex IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003729 mRNA binding IEA
 molecular_functionGO:0003730 mRNA 3"-UTR binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008494 translation activator activity IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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